Results 71 to 80 of about 775,483 (328)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Treatment of Multivariate Outliers in Incomplete Business Survey Data
Austrian Journal of Statistics, 2016 The distribution of multivariate quantitative survey data usually is not normal. Skewed and semi-continuous distributions occur often. In addition, missing values and non-response is common.
Marc Bill, Beat Hulliger
doaj +1 more source
Moments of Order Statistics from the Equicorrelated Multivariate Normal Distribution
The Annals of Mathematical Statistics, 1962 Let $Z_1, Z_2, \cdots, Z_n$ be jointly normally distributed random variables with $EZ_i = 0, EZ^2_i = 1, EZ_iZ_j = \rho, i \neq j, -1/(n - 1) \leqq \rho \leqq 1$. Let the collection of random variables $\{Z_i\}$ be ordered so that $Z^{(1)} \geqq Z^{(2)} \geqq \cdots \geqq Z^{(n)}$.
Owen, D. B., Steck, G. P.
openaire +3 more sources
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Robust multivariate nonparametric tests for detection of two-sample location shift in clinical trials. [PDF]
PLoS ONE, 2018 This article presents and investigates performance of a series of robust multivariate nonparametric tests for detection of location shift between two multivariate samples in randomized controlled trials.
Xuejun Jiang +4 more
doaj +1 more source
Exact asymptotic distribution of change-point mle for change in the mean of Gaussian sequences
, 2010 We derive exact computable expressions for the asymptotic distribution of the change-point mle when a change in the mean occurred at an unknown point of a sequence of time-ordered independent Gaussian random variables.
Fotopoulos, Stergios B. +2 more
core +1 more source
International Conference on Knowledge-Based Intelligent Information & Engineering Systems, 2016 In recent years, numerous papers dealing with extensions of Marshall-Olkin distributions have appeared. However, the Marshall- Olkin model is not yet a commonly used mathematical model in the field of risk analysis, even though it has been considered to ...
T. Yuge, M. Maruyama, S. Yanagi
semanticscholar +1 more source
Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas +7 more
wiley +1 more source
Power Estimation in Multivariate Analysis of Variance [PDF]
Tutorials in Quantitative Methods for Psychology, 2007 Power is often overlooked in designing multivariate studies for the simple reason that it is believed to be too complicated. In this paper, it is shown that power estimation in multivariate analysis of variance (MANOVA) can be approximated using a F ...
Jean François Allaire, Sylvain Chartier
doaj
Approximating Probability Densities by Iterated Laplace Approximations
, 2011 The Laplace approximation is an old, but frequently used method to approximate integrals for Bayesian calculations. In this paper we develop an extension of the Laplace approximation, by applying it iteratively to the residual, i.e., the difference ...
Ardia D. +3 more
core +1 more source