Results 121 to 130 of about 14,407 (260)

Multivariate polyharmonic spline interpolation

open access: yes, 2018
Let (OMEGA) be an open, bounded set in (//R)('n), and let A be a finite subset of (OMEGA). For f in H('k)((OMEGA)), where k > n/2, a spline s satisfying (-1)('k)(DELTA)('k)s(x) = 0 for x in (OMEGA)-A and solving the interpolation problem:; s(a) = f(a) a(epsilon)A; (f-s) (epsilon) H(,0)('k)((OMEGA));is shown to exist and to exhibit many of the ...
openaire   +3 more sources

Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller   +4 more
wiley   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

open access: yesBMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo   +9 more
wiley   +1 more source

Early evolutionary history of the seed

open access: yesBiological Reviews, EarlyView.
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman   +2 more
wiley   +1 more source

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo   +11 more
wiley   +1 more source

Accurate prediction of sepsis from pediatric emergency department to PICU using a machine-learning model. [PDF]

open access: yesFront Pediatr
Shi X   +10 more
europepmc   +1 more source

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