Results 211 to 220 of about 15,402,643 (297)

Long‐Term Risk of Rheumatoid Arthritis in Individuals With Autism Spectrum Disorder: A Population‐Based Matched Cohort Study

open access: yesAutism Research, EarlyView.
ABSTRACT To investigate the long‐term risk of rheumatoid arthritis (RA) among individuals with autism spectrum disorder (ASD), addressing potential immune comorbidity in ASD populations. A population‐based matched cohort was assembled using Swedish registers, including 46,164 individuals diagnosed with ASD between 1987 and 2017, matched to 4,634,895 ...
Evora Hailin Zhu   +10 more
wiley   +1 more source

Bayesian Conditional GAN for Unsupervised Anomaly Detection in Structural Health Monitoring Time-Series Dataset. [PDF]

open access: yesSensors (Basel)
Alemu YL   +7 more
europepmc   +1 more source

Biochar‐based fertilizers improve nutrient use efficiency in sunflower grown on a subtropical tidal soil

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Improving fertilizer use efficiency is essential for reducing environmental pollution, sustaining agricultural production, and maximizing the economic profitability of crop production systems. This study tested the hypothesis that the formulation strategy of biochar‐based fertilizers, rather than nutrient addition alone, is associated with ...
Md. Al‐Amin   +7 more
wiley   +1 more source

Flexible outlier detection in multicenter clinical trials. [PDF]

open access: yesJ Clin Transl Sci
Rigdon J   +7 more
europepmc   +1 more source

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim   +37 more
wiley   +1 more source

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu   +7 more
wiley   +1 more source

The integrated Lei‐CNS PBPK‐PD model effectively predicts clozapine brain disposition and D2 receptor occupancy in humans

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Clozapine, used for treatment‐resistant schizophrenia, has a narrow therapeutic window and highly variable plasma pharmacokinetics (PK), necessitating careful monitoring. Direct measurement of unbound brain PK in humans is unethical. To develop a physiologically based pharmacokinetic–pharmacodynamic (PBPK‐PD) model to predict clozapine brain ...
Mengxu Zhang   +3 more
wiley   +1 more source

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