Results 221 to 230 of about 15,402,643 (297)

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

British Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said, Robert B. de Mooij, Dian Jiao, Reitze J. Ovelgonne, Rami Biram, Juan Delgado‐SanMartin, Alexander M. K. Rothman, Sofia S. Villar, Andreas A. Roussakis, Jurjan Aman, Ron A. A. Mathôt, Eleonora L. Swart, Martin R. Wilkins, Imke H. Bartelink   +13 more
wiley   +1 more source

Treatment patterns and clinical outcomes in chronic myeloid leukemia treated with second-line nilotinib-association of molecular milestones and prognostic scores with deep molecular response: a real-world retrospective cohort study. [PDF]

Sao Paulo Med J
Ćojbašić I, Tijanić I, Ćojbašić Ž.   +2 more
europepmc   +1 more source

Addressing racialised awarding gap in higher education: Insights from personal tutors

British Educational Research Journal, EarlyView.
Abstract Situated within a wider cross‐institutional research project, this article provides an in‐depth case study of one higher education (HE) institution, focusing on how personal tutors make sense of racialised degree awarding disparities for both undergraduate and postgraduate students, how they perceive their responsibilities, the challenges and ...
Benjamin Ajibade, Rick Hayman, Angela Hibbs, Josephine Gabi   +3 more
wiley   +1 more source

New-Onset Diabetes After Pancreaticoduodenectomy: 3D Volumetric Analysis and Evaluation of Preoperative Metabolic Load. [PDF]

J Clin Med
Aydın O, Korkmaz YY, Altay M, Kudaş İ, Baş S, Bostancı Ö, Kinaci E.   +6 more
europepmc   +1 more source

How curriculum modifications shape educational pathways: Evidence from linked administrative data in Switzerland

British Educational Research Journal, EarlyView.
Abstract The increasing heterogeneity of learning needs and preconditions in inclusive mainstream classrooms entails that not all learners are equally able to meet the regular learning objectives. In response, various integrative measures have been implemented to tailor instruction to students' individual needs.
Robin Benz, Caroline Sahli Lozano, Esperanza Marx   +2 more
wiley   +1 more source

Trend-Conditioned Residual Learning for Early Fault Warning in Nonstationary Multi-Sensor Oil Monitoring. [PDF]

Sensors (Basel)
Li H, Chen Y, Wang Y, Wu C.
europepmc   +1 more source

Preoperative HALP index as a predictor of in-hospital mortality after type A aortic dissection surgery: a retrospective cohort study. [PDF]

Ann Med
Chen Z, Lin Z, Liu Q, Chen P, Chen H.
europepmc   +1 more source

Renal injury and hypocalcaemia in newborns with birth asphyxia at a tertiary care centre: a prospective observational study. [PDF]

BMJ Paediatr Open
Tard SC, Tanwar GS, Berwal PK.
europepmc   +1 more source

Health-Seeking Behaviors After Acute Respiratory Infection Among Urban and Rural Residents and Different Age Groups: Cross-Sectional Questionnaire Study. [PDF]

J Med Internet Res
Lai M, Yan K, Chen Y, Chen D, Xiang S, Xu A, Wang Y.   +6 more
europepmc   +1 more source

Early Local Treatment Delays Multiple Metastases in Non-Small Cell Lung Cancer With Solitary Distant Metastasis: A Multicenter Retrospective Cohort Study. [PDF]

MedComm (2020)
Miao K, Lei S, Zheng X, Yang S, Li Y, Chen S, Miao Q, Zhang L, Zou Z, Xu H, Lin G.   +10 more
europepmc   +1 more source