Diabetes is an independent risk factor for gallstones. It upregulates CXCR2 expression in hepatic neutrophils, stimulating the formation of NETs that disrupt hepatocellular tight junctions and the liver‐bile barrier. NETs enter bile to accelerate gallstone development, while sarcosine inhibits CXCR2 and NETs production, effectively reducing diabetes ...
Chao Shi +10 more
wiley +1 more source
Rapid measurement of soluble xylo-oligomers using near-infrared spectroscopy (NIRS) and multivariate statistics: calibration model development and practical approaches to model optimization. [PDF]
Tillman Z, Gray K, Wolfrum E.
europepmc +1 more source
Searching for Solvents with an Increased Carbon Dioxide Solubility Using Multivariate Statistics. [PDF]
Bystrzanowska M +3 more
europepmc +1 more source
This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin +5 more
wiley +1 more source
Multivariate statistical assessment of polluted soils
Simeonov Vasil +3 more
doaj +1 more source
Assessment of Beeswax Adulteration by Paraffin and Stearic Acid Using ATR-IR Spectroscopy and Multivariate Statistics-An Analytical Method to Detect Fraud. [PDF]
Chatzipanagis K, Omar J, Sanfeliu AB.
europepmc +1 more source
Water quality assessment based on multivariate statistics and water quality index of a strategic river in the Brazilian Atlantic Forest. [PDF]
de Andrade Costa D +3 more
europepmc +1 more source
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
Untargeted Metabolomic Analysis Combined With Multivariate Statistics Reveal Distinct Metabolic Changes in GPR40 Agonist-Treated Animals Related to Bile Acid Metabolism. [PDF]
Doerfler H +3 more
europepmc +1 more source
A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang +5 more
wiley +1 more source

