Results 51 to 60 of about 1,093,856 (281)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Urban Landscape Structure of a Fast-Growing African City: The Case of Niamey (Niger)

open access: yesUrban Science, 2019
Combining multivariable statistics and geostatistics with landscape metrics, we attempted to quantify the spatial pattern of urbanization in the city of Niamey, Niger.
Jean-Pierre Rossi, Gauthier Dobigny
doaj   +1 more source

Hydrogeochemistry of Groundwater from Kazaure Area, NW Nigeria using Multivariate Statistics [PDF]

open access: yesE3S Web of Conferences, 2019
This study was aimed at understanding the factors affecting groundwater for the benefit of water resources management. Groundwater collected from 18 sites over an area of 770 Km2 was analysed.
Ado Musa   +3 more
doaj   +1 more source

Moments of minors of Wishart matrices

open access: yes, 2008
For a random matrix following a Wishart distribution, we derive formulas for the expectation and the covariance matrix of compound matrices. The compound matrix of order $m$ is populated by all $m\times m$-minors of the Wishart matrix.
Drton, Mathias   +2 more
core   +2 more sources

Limit theorems for linear eigenvalue statistics of overlapping matrices [PDF]

open access: yes, 2015
The paper proves several limit theorems for linear eigenvalue statistics of overlapping Wigner and sample covariance matrices. It is shown that the covariance of the limiting multivariate Gaussian distribution is diagonalized by choosing the Chebyshev ...
Kargin, Vladislav
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

A Multivariate Study of Morphological Characters for Echinocactus horizonthalonius and E. texensis (Cactaceae) and Description of a New Subspecies, E. horizonthalonius subsp. australis

open access: yesDiversity, 2022
A study was conducted to ascertain the taxonomic validity of the endangered taxon Echinocactus horizonthalonius var. nicholii and whether there may be other groups of populations worthy of subspecies status within the range of the species.
Marc A. Baker
doaj   +1 more source

Random fields of multivariate test statistics, with applications to shape analysis

open access: yes, 2008
Our data are random fields of multivariate Gaussian observations, and we fit a multivariate linear model with common design matrix at each point. We are interested in detecting those points where some of the coefficients are nonzero using classical ...
Taylor, J. E., Worsley, K. J.
core   +3 more sources

Tests for covariance matrices, particularly for high dimensional data [PDF]

open access: yes, 2010
Test statistics for sphericity and identity of the covariance matrix are presented, when the data are multivariate normal and the dimension, p, can be larger than the sample size, n.
Ahmad, M. Rauf
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

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