Results 51 to 60 of about 46,796 (242)

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

Time series analysis of mumps and meteorological factors in Beijing, China

BMC Infectious Diseases, 2019
Background Over the past decades there have been outbreaks of mumps in many countries, even in populations that were vaccinated. Some studies suggest that the incidence of mumps is related to meteorological changes, but the results of these studies vary ...
Yu Hao, Ran-ran Wang, Ling Han, Hong Wang, Xuan Zhang, Qiao-ling Tang, Long Yan, Juan He   +7 more
doaj   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Mumps virus Enders strain is sensitive to interferon (IFN) despite encoding a functional IFN antagonist

, 2009
Although the Enders strain of mumps virus (MuV) encodes a functional V protein that acts as an interferon (IFN) antagonist, in multi-cycle growth assays MuV Enders grew poorly in naive ('IFN-competent' Hep2) cells but grew to high titres in 'IFN ...
Rima, B K, Andrejeva, Jelena, K. Lemon, B. K. Rima, Duprex, P, W. P. Duprex, M. C. Galiano, Galiano, M, J. Andrejeva, D. F. Young, R. E. Randall, Young, D F, Lemon, K, Chen, Y-H, Y.-H. Chen, Randall, Richard Edward   +15 more
core   +1 more source

Can Hormonal Therapy Improve the Outcomes of mTESE in Patients With Non‐Obstructive Azoospermia?

Andrology, EarlyView.
ABSTRACT Background Non‐obstructive azoospermia (NOA) represents the most severe form of male infertility. Hypogonadism is common in NOA patients, and normal testosterone (T) levels are considered essential for spermatogenesis. Fertility‐preserving hormonal therapy (FpHT) has been proposed to optimize hormonal milieu and improve sperm retrieval rates ...
Mattia Anfosso, Maria Schubert, Jann‐Frederik Cremers, Sabine Kliesch, Michael Zitzmann, Simone Bier   +5 more
wiley   +1 more source

Genetic characteristic of mumps virus from 2012 to 2016 and its serum antibody level among general healthy population during 2018–2020 in Jiangsu Province, China

BMC Infectious Diseases
Mumps is a vaccine-preventable disease with high contagious capability. Its incidence declined rapidly since one dose of mumps vaccine was introduced into Expanded Program of Immunization (EPI) in 2008 in China. Nonetheless, the outbreaks of mumps remain
Xiuying Deng, Ying Hu, Peishan Lu, Zhiguo Wang, Hongxiong Guo   +4 more
doaj   +1 more source

Factors associated with mumps meningitis and the possible impact of vaccination [PDF]

Korean Journal of Pediatrics, 2016
PurposeMumps meningitis is a common complication of mumps infection; however, information on mumps meningitis in the postvaccine era is limited. The purpose of the present study was to determine factors associated with mumps meningitis and to discuss the
Kyuyol Rhie, Heung-Keun Park, Young-Soo Kim, Jung Sook Yeom, Ji Sook Park, Ji-Hyun Seo, Eun Sil Park, Jae-Young Lim, Chan-Hoo Park, Hyang-Ok Woo, Hee-Shang Youn   +10 more
doaj   +1 more source

Ethical Considerations Regarding the Vaccination of Children—The Power Dynamics Between Doctors and Parents

Acta Paediatrica, EarlyView.
ABSTRACT While childhood vaccination programmes provide outstanding contributions to improving health, they can also pose challenges through the interactions between parents and healthcare. This paper focuses on the ethical dimensions of interactions between healthcare professionals and parents. Since the knowledge that professionals possess creates an
Mikael Sandlund, Ingemar Engström, Anders Castor   +2 more
wiley   +1 more source

Genomic tools for post-elimination measles molecular epidemiology using Canadian surveillance data from 2018–2020

Frontiers in Microbiology
IntroductionMeasles is caused by the highly infectious measles virus, MeV, for which there is an effective vaccine. Monitoring of progress of measles elimination requires enhanced surveillance and tracking of MeV strains, including documenting the ...
Joanne Hiebert, Vanessa Zubach, Helene Schulz, Alberto Severini   +3 more
doaj   +1 more source

Introduction of Two-Dose Mumps-Containing Vaccine into Routine Immunization Schedule in Quzhou, China, Using Cox-Proportional Hazard Model

Journal of Immunology Research, 2021
Mumps is a vaccine-preventable disease caused by the mumps virus, but the incidence of mumps has increased among the children who were vaccinated with one-dose measles-mumps-rubella (MMR) in recent years.
Zhiying Yin, Canjie Zheng, Quanjun Fang, Xiaoying Gong, Guoping Cao, Junji Li, Ziling Xiang, Wei Song   +7 more
doaj   +1 more source