Recombinant mumps virus as a cancer therapeutic agent
Molecular Therapy: Oncolytics, 2016 Mumps virus belongs to the family of Paramyxoviridae and has the potential to be an oncolytic agent. Mumps virus Urabe strain had been tested in the clinical setting as a treatment for human cancer four decades ago in Japan.
Arun Ammayappan +2 more
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Glycosylation as a strategic mechanism for measles virus and mumps virus immune evasion [PDF]
Frontiers in ImmunologyGlycosylation of viral surface proteins by host cell factors is one strategy paramyxoviruses employ to evade the host’s immune system during infection. Viral glycosylation thus has the potential for innate and adaptive immune modulation.
Catalina Galvan +2 more
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Genetic characteristic of mumps virus from 2012 to 2016 and its serum antibody level among general healthy population during 2018–2020 in Jiangsu Province, China [PDF]
BMC Infectious DiseasesMumps is a vaccine-preventable disease with high contagious capability. Its incidence declined rapidly since one dose of mumps vaccine was introduced into Expanded Program of Immunization (EPI) in 2008 in China. Nonetheless, the outbreaks of mumps remain
Xiuying Deng +4 more
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The power of mumps virus: Matrix protein activates apoptotic pathways in human colorectal cell lines. [PDF]
PLoS ONE, 2023 New therapeutic approaches can significantly impact the control of colorectal cancer (CRC), which is increasing worldwide. In this study, we investigated the potential of targeting viral proteins to combat cancer cells.
Solmaz Morovati +4 more
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Combining genomics and epidemiology to track mumps virus transmission in the United States
PLoS Biology, 2020 Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and the relationship between these and prior outbreaks.
Shirlee Wohl +2 more
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Repeated introductions and intensive community transmission fueled a mumps virus outbreak in Washington State [PDF]
eLife, 2021 In 2016/2017, Washington State experienced a mumps outbreak despite high childhood vaccination rates, with cases more frequently detected among school-aged children and members of the Marshallese community.
Louise H Moncla +9 more
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Exploration of microRNAs as transcriptional regulator in mumps virus infection through computational studies [PDF]
Scientific ReportsMumps is a common childhood infection caused by the mumps virus (MuV). Aseptic meningitis and encephalitis are usual symptoms of mumps together with orchitis and oophoritis that can arise in males and females, respectively.
Mubashir Hassan +4 more
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Polypeptides of mumps virus [PDF]
Journal of Virology, 1976 Mumps virus was propagated in the extra-embryonic fluids of embryonated chicken eggs and was labeled by cionjection of radioactively labeled amino acids. The virus was purified by density gradient centrifugation, and its polypeptides were analyzed by polyarylamide gel electrophoresis.
S C, Jensik, S, Silver
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Introduction. Registration of regular epidemic outbreaks of mumps infection among young people, difficulties in the clinical diagnosis of the disease, the presence of specific clinical manifestations in adults with a severe course of infection make it ...
Vadislav V. Semerikov +5 more
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BMC Infectious Diseases, 2021 Background From October 2019–March 2020, several clusters of mumps cases were identified in the Netherlands. Our objective was to describe cluster-associated mumps virus transmission using epidemiological and molecular information in order to help future
Anita A. Shah +6 more
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