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Intracellular processing of mumps virus glycoproteins
Virology, 1988Using newly isolated monoclonal antibodies (MoAb) directed to the hemagglutinin-neuraminidase (HN) and the fusion (F) glycoproteins of mumps virus, we have analyzed post-translational modification of both glycoproteins. The HN glycoprotein synthesized as a monomer slowly acquires immunoreactivity with a monoclonal antibody (MoAb) to the HN in ...
Kaoru Takeuchi+2 more
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Analysis of mumps virus defectiveness in vitro
Life Sciences, 1978Abstract The efficiency of mumps virus replication (EOR) was determined by comparing the multiplicity of infectious input (MOI) with the multiplicity of viral production (MOP). The replication kinetics of low passage wild, high passage laboratory and attenuated vaccine virus were evaluated using regular stock and cloned pools of virus (Table).
Hawley L. Martin+5 more
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Live, Attenuated Mumps-Virus Vaccine
New England Journal of Medicine, 1968Abstract Jeryl-Lynn strain (B level) live, attenuated mumps-virus vaccine was administered to 6283 initially susceptible children and 163 adults, including 132 males. There was no evident clinical reaction to the vaccine either in adults or in children including infants.
Eugene B. Buynak+3 more
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1988
Disease: Mumps. Etiologic Agent: Mumps virus. Source: Infected humans spread the virus by droplet infection of infected saliva to nonim mune contacts. Clinical Manifestations: Generalized systemic infection with fever, swelling of parotid glands, and frequent involvement of the central nervous system.
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Disease: Mumps. Etiologic Agent: Mumps virus. Source: Infected humans spread the virus by droplet infection of infected saliva to nonim mune contacts. Clinical Manifestations: Generalized systemic infection with fever, swelling of parotid glands, and frequent involvement of the central nervous system.
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Salivary IgA Antibodies to Mumps Virus During and After Mumps
Journal of Infectious Diseases, 1981Legend. Titers of secretory IgA antibody to mumps virus were determined by radioimmunoassay on serial sour candy-stimulated saliva samples from 14 children, 3.5-11 years of age, who were recovering from mumps. Fourfold dilutions of supernatant from frozen samples, inactivated at 56 C for 1 hr and centrifuged, were tested against mumps and control ...
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Treatment of human cancer with mumps virus
Cancer, 1974Based on confirmation that slightly toxic mumps virus having a strong affinity with mankind has a carcinostatic effect, it was used in cancer. As priority was put not on healing but on reconfirmation of its effectiveness against human cancer and on its mode of administration, patients mostly received only small amounts of the virus. Of 90 patients with
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The Concentration of Mumps Virus
Journal of Infectious Diseases, 1949Esther Carson, George F. Forster
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Viremia in Human Mumps Virus Infections
Archives of Internal Medicine, 1958The isolation of mumps virus from the blood of a patient has been reported on but one occasion, in 1949. 1 The lack of subsequent confirmatory reports, then, leaves the question of viremia in mumps somewhat in doubt. The present paper reports three subsequent isolates from the sera of two patients.
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