Results 221 to 230 of about 776,222 (355)

Small‐Molecule Activation of mRNA Translation by Click‐to‐Release Reaction in Cells

Angewandte Chemie, EarlyView.
A new method to control mRNA activity using bioorthogonal click‐to‐release reactions is presented. The 5′ cap is modified with a trans‐cyclooctene (TCO) that quickly reacts with hydroxyaryl‐tetrazines and efficiently releases the native cap 0. TCO‐capped mRNAs are initially translationally inactive but can be activated with non‐toxic, cell‐permeable ...
Tess Vosman, Friedrich Burba, Martin Sumser, Milan Vrabel, Hannes Mikula, Andrea Rentmeister   +5 more
wiley   +2 more sources

Recommended Venue: The International Youth Library in Munich

, 2015
Petra Rauschert
openalex   +1 more source

KLAUS WITTSTADT, Nuntius Atilio Amalteo (1606 September-1607 September), 1 vol. de LXXXII + 394 págs. Nuntiaturberichte aus Deutschland, n.º IV /1, (Hrsg), Görres-Gesellschaft, Ed. Ferdinand Schöningh, Munich-Paderborn-Viena, 1975

, 2018
José María González del Valle
openalex   +2 more sources

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

Advanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna, Thomas Mayer, Di Zhang, Matthias Marczynski, Carolin A. Rickert, Fabio Henkel, Lennart J. K. Weiss, Friedrich C. Simmel, Yuxia Luan, Oliver Lieleg   +9 more
wiley   +1 more source

Assessment of early-phase [¹⁸F]florbetaben images as a proxy for brain metabolism in mouse models of Alzheimer's disease. [PDF]

J Cereb Blood Flow Metab
Gröger R, Englert AL, Lalia M, de Weerd L, Rovere M, Kunze L, Palumbo G, Wind-Mark K, Fixemer S, Roemer-Cassiano SN, Franzmeier N, Höglinger G, Zwergal A, Tahirovic S, Werner RA, Brendel M, Gnörich J.   +16 more
europepmc   +1 more source

The Polarium at Munich Zoo [PDF]

, 1987
Hegel, G. von, Rau, B., Wiesner, Henning
core  

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

Advanced NanoBiomed Research, EarlyView.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo, Simone Micalizzi, Girish Pattappa, Philipp Stahlhut, Jürgen Groll, Carmelo De Maria, Denitsa Docheva, Giovanni Vozzi   +7 more
wiley   +1 more source

Stereotactic Radiotherapy for Metastatic Anaplastic Thyroid Cancer: A Single-center Experience and Systematic Review. [PDF]

In Vivo
Rennollet R, Gurtner R, Belka C, Spitzweg C, Rauch J, Käsmann L.   +5 more
europepmc   +1 more source

Prognostic impact of radiotherapy timing in WHO grade 2 and 3 meningiomas utilizing an integrated molecular-morphologic classification. [PDF]

J Neurooncol
Delbridge C, Hou HX, Hielscher T, Wiestler B, Negwer C, Schenck L, Peeken J, Diehl C, Borm K, Krieg S, Aftahy KA, Leiss SM, Schmidt-Graf F, Mitsdörffer M, Yakushev I, Von Deimling A, Gempt J, Meyer B, Combs SE, Sahm F, Bernhardt D.   +20 more
europepmc   +1 more source

Molekulare Modelle intermetallischer Phasen: Selektive Alkylamid‐Ligand‐Entschützung steuert die Bildung von Co/Ga‐Clustern

Angewandte Chemie, EarlyView.
Der bimetallische M14‐Cluster [Co3Ga2]H(μ2‐GaTMP)9 wurde durch einen ko‐reduktiven Ansatz erzielt. Dieser Ansatz nutzt Mg und H2, um den Ga‐TMP‐Liganden selektiv zu entschützen und das TMP abzufangen, was zur Bildung eines gemischtmetallischen Co/Ga Clusterkerns führt, was diesen zu einem strukturellen Vertreter eines vergleichbaren Gegenstücks der ...
Fabrizio E. Napoli, Raphael Bühler, Johannes Stephan, Samia Kahlal, Jean‐Yves Saillard, Christian Gemel, Roland A. Fischer   +6 more
wiley   +1 more source