Results 121 to 130 of about 964,068 (308)

Anti-Corruption Law in Local Government: Legal Issues related to Ordinance-Design and Municipal-Level Anti-Corruption Agencies in Macedonia [PDF]

open access: yes
Macedonian municipalities should pass anti-corruption ordinances in order to reduce corruption. The paper reviews the legal issues involved in drafting such ordinances and provides legal advisors to local councils with the legal and economic analysis ...
Bryane Michael, Linacre College (Oxford) and Stephen Mendes, European Border Assistance Mission to Moldova and Ukraine (EUBAM)
core  

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

open access: yesAdvanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang   +7 more
wiley   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

open access: yesAdvanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She   +14 more
wiley   +1 more source

Analysis of cost and effectiveness of treatment in benign paroxysmal positional vertigo

open access: yesChinese Medical Journal, 2019
Ya-Li Wang   +6 more
doaj   +1 more source

Intra-regional Disparity and Municipal Merger: Case Study in Fukuoka Prefecture [PDF]

open access: yes, 2013
This study examines intra-regional disparity and municipal merger in Fukuoka Prefecture. Fukuoka Prefecture (Fukuoka-ken) is a prefecture of Japan located on Kyushu Island.
Sakamoto, Hiroshi
core  

Single‐Cell RNA Sequencing of Human Lung Tissues Reveals Metallothionein‐Positive T Cells as a Novel Potential Marker of Susceptibility to Chronic Obstructive Pulmonary Disease

open access: yesAdvanced Science, EarlyView.
Using single‐cell RNA sequencing of lung samples and flow cytometry of peripheral blood, we identified a novel T cell subset with high metallothionein (MT) expression. These MT‐high T cells suppress CD8+ T cell cytotoxicity and are progressively depleted from healthy controls to chronic obstructive pulmonary disease (COPD) patients, positioning them as
Zengqing Liu   +23 more
wiley   +1 more source

POPULATION DYNAMICS, AGGLOMERATION ECONOMIES AND MUNICIPAL SIZE: A LONG-TERM ANALYSIS [PDF]

open access: yesJournal of Urban and Regional Analysis, 2019
Under the hypothesis that modifications in municipal boundaries and creation (or suppression) of new administrative units reflect a progressive adjustment toward a more balanced distribution of population over space, the present study investigates the ...
Maria Teresa CIOMMI   +2 more
doaj  

Urban Transformation as a tool for Disaster Mitigation [PDF]

open access: yes
Urban transformation projects are prepared with the purpose to sanitize decayed areas, to make cities beautiful and to create economic vitality. Since natural hazards threaten large metropolitan areas, urban transformation is pronounced together to ...
Handan Turkoglu, Seda Kundak
core  

Taman Seri Serdang a clean zone [PDF]

open access: yes, 2012
IN conjunction with the Clean Zone competition for 2011/2012 session, the Subang Jaya Municipal Council (MPSJ) recently announced Taman Seri Serdang as a Clean Zone ...
New Straits Times, Fairuz Mohd Shahar
core  

High‐Performance Ternary Organic Solar Cells via Isomeric Engineering of Nonfullerene Guest Acceptors

open access: yesAdvanced Science, EarlyView.
Two isomeric nonfullerene acceptors, BTP‐γ‐Br and BTP‐δ‐Br, were designed to investigate their effects on the optoelectronic properties and photovoltaic performance of ternary blends. Incorporating BTP‐γ‐Br into the D18:N3 binary system can enhance film crystallinity and suppress charge recombination, achieving a high PCE of 19.2% and a certified JSC ...
Zhenzhong Pan   +8 more
wiley   +1 more source

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