Results 141 to 150 of about 964,068 (308)
Unintended Consequences of Water Legislation [PDF]
The population of Texas is expected to double by 2060. The Texas Lower Rio Grande Valley is one area in which alternative water sources and potable treatment methods are being sought to support a rapid population growth.
Yow, Shauna
core +1 more source
Advanced Science, EarlyView.This study reveals that PDZK1 loss impairs ULK1‐mediated lipophagy, driving lipid droplet accumulation and sunitinib resistance in clear cell renal cell carcinoma. PDZK1 inhibits LEF1 nuclear translocation, enhancing ULK1 transcription. Pharmacological ULK1 activation resensitizes resistant tumors to sunitinib.
Xuan Qi +11 more
wiley +1 more source
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Dengue Hemorrhagic Fever Tranmission Risk Level on Three Local Health Center in Three Endemic District in South Sulawesi Province, Indonesia [PDF]
, 2017 . The aim of this research is to determine of transmission risk level of Dengue Hemorrhagic Fever (DHF) endemic area in District of Bone, Municipal of Palopo, and Municipal of Makassar, South Sulawesi province.
Andiarsa, D. (Dicky) +1 more
core
Advanced Science, EarlyView.Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian +5 more
wiley +1 more source
ANALISIS KEBIJAKAN PENGELOLAAN SAMPAH PERKOTAAN DI KOTA MALANG
Jurnal Ilmu Kesehatan Masyarakat, 2015 Solid waste is important issue in urban area that is faced continously in line with increase number of residents and improvement of development activity. Every day 2-3 litres of solid waste is produced by everyone in urban area.
Isa Ma'rufi, Khoiron Khoiron
doaj
Hydrogeological and hydrochemical investigation of denizli municipality urban area
, 2005 Within the urban area of Denizli Municipality and its vicinity, the hydraulic picture is a combination of three aquifer systems in the (a) alluvium (b) alluvial fan and (c) the Neogene lacustrine deposits. At different locations free surface, semi-confined and confined aquifers are observed.
Gokgoz, A +3 more
openaire +2 more sources
Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis
Advanced Science, EarlyView.Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu +13 more
wiley +1 more source
Journal of NanobiotechnologyBackground Reactive oxygen species (ROS)-mediated pyroptosis provides a robust strategy for overcoming apoptosis resistance in breast cancer therapy. Nevertheless, the low efficiency of pyroptosis remains an undeniable challenge. Overcoming this obstacle
Xiaoyan Li +7 more
doaj +1 more source
Contributing factors to high prevalence of hearing impairment in the Elias Motsoaledi Local Municipal area, South Africa: A rural perspective. [PDF]
S Afr J Commun Disord, 2019 Joubert K, Botha D.
europepmc +1 more source