Results 121 to 130 of about 255,065 (314)

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

open access: yesAdvanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang   +16 more
wiley   +1 more source

Research on the conceptual foundations of innovative financing instruments for territorial communities’ infrastructure: green bonds

open access: yesФінансово-кредитні системи: перспективи розвитку.
The article examines the conceptual foundations for the development of the green bond market in Ukraine as a tool for financing the reconstruction of territorial communities’ infrastructure, particularly under martial law conditions.
Galina Daudova   +2 more
doaj   +1 more source

Toward Equal Delivery of Municipal Services in the Central Cities [PDF]

open access: yes, 1976
Urban living has become inevitable for most Americans in central cities and government assistance has risen steadily to help the masses crowded in the urban complex. Legislation has been aimed at equalizing the opportunity for employment, decent housing,
Bond, Kenneth W.
core   +1 more source

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

open access: yesAdvanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang   +22 more
wiley   +1 more source

Why Did Auction Rate Bond Auctions Fail During 2007-2008? [PDF]

open access: yes
The auction rate bond market grew from inauspicious beginnings in 1985 to representing a significant fraction of the municipal bond market in 2007 with a total of 603 issuances that year raising more than $35 billion in capital. Since March of 2008 not a
Alessio Saretto   +2 more
core  

Magnetic Anisotropy Modulation via van der Waals Gap Engineering in 2D Ferromagnet Fe4GeTe2

open access: yesAdvanced Science, EarlyView.
This study demonstrates a new route to control magnetic anisotropy in 2D ferromagnets via van der Waals gap engineering. In Fe4GeTe2, an interface‐induced vdW gap expansion is found to anomalously enhance in‐plane magnetic anisotropy while suppressing the spin reorientation transition.
Weiran Xie   +13 more
wiley   +1 more source

Investment decision, legal certainty and its determinant factors: evidence from the Indonesia Stock Exchange

open access: yesCogent Business & Management
In the context developing country, the relationship between legal certainty and investment decision is still an underexplored yet important context. This study investigates the effect of independent judicial system, legal culture, and the existence of ...
Benny Hutahayan   +3 more
doaj   +1 more source

The Impact of Pensions on State Borrowing Costs [PDF]

open access: yes
Municipal bond prices are tumbling and rates rising just as public borrowers face pressure to refinance deals cut during the financial crisis. At the same time, the funded status of public pension plans has declined, and states and localities will have ...
Alicia H. Munnell   +2 more
core   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

open access: yesAdvanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang   +7 more
wiley   +1 more source

Brazilian Breast Cancer Care Network: the perspective of health managers

open access: yesRevista Brasileira de Enfermagem
Objective: To analyze the organization of the Brazilian Breast Cancer Care Network, according to the perspective of managers of the Coordenadoria Regional de Saúde Sudeste (Southeast Regional Coordination of Health) of the city of São Paulo.
Rosely Erlach Goldman   +5 more
doaj   +1 more source

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