Results 101 to 110 of about 1,251,769 (293)

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu   +10 more
wiley   +1 more source

Municipal Bonds at Bucharest Stock Exchange: What the Correlations are Revealing?

open access: yesStudia Universitatis Babeş-Bolyai Negotia
Article history: Received: May 15, 2024; Reviewed: June 14, 2024; Accepted: June 21, 2024; Available online: June 30, 2024. As highlighted by Pop & Georgescu (2024), the Romanian academic literature concerning municipal bonds is sparse, while the ...
Cornelia POP, Maria-Andrada GEORGESCU
doaj   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han   +24 more
wiley   +1 more source

Municipal Bonds And Tax Arbitrage: A Cointegration Analysis

open access: yes, 2000
This article presents a new, cointegration approach to test a tax arbitrage opportunity in holding municipal bonds. Noticing that the variables of interest are nonstationary, two alternative cointegration tests are used to examine the relationship that ...
Lee, Junsoo   +2 more
core   +1 more source

Lactate‐Induced K370 Lactylation of STING Inhibits STING‐TBK1 Signaling and Dampens Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu   +11 more
wiley   +1 more source

Municipal Bonds as a Financial Source of Local Development [PDF]

open access: yes, 2007
A subject of this article is to present the municipal bonds as a financial source of local development. Whereas they play an important role in development of local infrastructure in the developed countries their importance barely begins to increase in ...
Dębski, Wiesław
core   +1 more source

An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li   +11 more
wiley   +1 more source

Challenge of financing physical infrastructure and services in Brihanmumbai municipal corporation [PDF]

open access: yes
Mumbai city is a financial capital of country but at present it is facing acute pressure of rise in population and inadequate infrastructure facilities and services.
Rode, Sanjay
core  

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

open access: yesAdvanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He   +10 more
wiley   +1 more source

The process of issues of corporate and municipal bonds

open access: yes, 2006
Bakalářská práce s názvem „Proces emise podnikových a komunálních dluhopisů‘‘ pojednává o způsobu emise dluhopisů a podrobně analyzuje proces emise těchto dluhopisů. Nejprve je pozornost zaměřena na dluhopisy obecně, jejich náležitosti a jednotlivé druhy
Zukalová, Monika
core   +1 more source

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