Results 41 to 50 of about 1,655,459 (311)

Municipal Financing and Infrastructure: A Critical Analysis of the Cities in West Bengal

open access: yesSpace and Culture, India, 2021
Cities, acting as engines of economic growth and generators of public finance for development, will usher in an urban revolution in the developing world.
Priya Chowdhury, Gopa Samanta
doaj   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

open access: yesAdvanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang   +19 more
wiley   +1 more source

Descentralização e endividamento municipal: formas, limites e possibilidades

open access: yesNova Economia, 2009
The objective of this article is to discuss alternatives to finance investments by municipalities. In general, current revenues are insufficient to finance large investments, what brings about the necessity of municipal indebtedness.
Amaury Patrick Gremaud   +1 more
doaj  

Coalition effects on financial and service delivery performance in metropolitan municipalities in Gauteng

open access: yesJournal of Local Government Research and Innovation
Background: The South African electoral system does not favour a winner-takes-all situation. It is designed for a possible political coalition government on the basis of an electoral outcome below the 50+1 at the national, provincial and local government
Abongile Zweni   +2 more
doaj   +1 more source

Tax administration reform in transition: the case of Croatia [PDF]

open access: yes, 1998
This Occasional Paper reports the research results of a project on the tax administration in Croatia conducted by the Institute of Public Finance in Zagreb for the Croatian Tax Administration.
Ott, Katarina, Katarina Ott
core   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

Who leads, who lags? Inter-urban inequities in European climate adaptation funding and financing

open access: yesEnvironmental Research Letters
Despite increased attention to climate finance in urban adaptation, empirical data on the socio-political processes shaping funding accessibility, allocation, and their implications for inter-urban adaptation progress remains limited.
Kayin Venner   +5 more
doaj   +1 more source

Financial crisis and tax capacity in South Africa’s local government: A review of budgetary failures and structural constraints

open access: yesJournal of Local Government Research and Innovation
Background: South African municipalities have been experiencing increased fiscal distress for over the past two decades, with some approaching collapse.
Vuyani G. Langa, Sanjay Balkaran
doaj   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie   +14 more
wiley   +1 more source

Urban governance and finance in India. [PDF]

open access: yes
Over 330 million people live in India's cities; 35 cities have a population of over a million and three (Mumbai, Delhi, and Kolkata) of the 10 largest metropolises in the world are in India.
M. Govinda Rao, Bird, Richard M.
core   +2 more sources

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