Results 51 to 60 of about 1,655,459 (311)

Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly

Advanced Science, EarlyView.
LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang, Xin Wang, Yilan Teng, Zhicheng Wu, Jing Fan, Hongwen Zhu, Peng Dai   +6 more
wiley   +1 more source

Passive Metasurface Tweezers for Multi‐Scale Orbital Transport and Trapping on Elastic Plates

Advanced Science, EarlyView.
Passive labyrinthine phase encoding converts single‐channel excitation into localized flexural‐wave vortices with programmable orbital angular momentum. The resulting vortex fields enable cross‐scale particle manipulation, including orbital transport, central confinement, and rotational actuation.
Zeyang Bi, Zhiqiang Li, Yunkang Ren, Yugui Peng, Xuefeng Zhu, Liuxian Zhao, Jun Yang, Chuanxing Bi   +7 more
wiley   +1 more source

IMPROVING FINANCIAL MECHANISM OF THE MUNICIPAL PLANNING AS THE BASIS OF ECONOMIC ACTIVITY INCREASING LOCAL GOVERNMENT

Вестник Северо-Кавказского федерального университета, 2022
The article develops a system of factors determining the fiscal capacity of the municipality, given the measures of increase of efficiency of budget expenditures of the RF subject, provided in the form of intergovernmental transfers analyzed the specific
Nakhapu Ibragimova
doaj  

The need of municipal fiscal equalization reform in Estonia. Kohalike omavalitsuste rahastamise tasakaalustamise reformi vajalikkus Eestis

Eesti Majanduspoliitilised Väitlused, 2010
Estonian municipalities have to perform a broad range, while their fiscal resources are often limited in comparison to functions and large disparities in fiscal capacity prevail among them.
Peter Friedrich, Chang Woon Nam, Janno Reiljan   +2 more
doaj   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

ECONOMIC AND LEGAL PRINCIPLES FOR ENSURING THE FINANCIAL SUSTAINABILITY OF LOCAL SELF-GOVERNMENT BODIES IN UKRAINE: CHALLENGES AND PROSPECTS

Baltic Journal of Economic Studies
This article examines the economic and legal principles that ensure the financial sustainability of local self-government bodies in Ukraine, particularly in the context of decentralisation reforms and mounting budgetary challenges.
Denys Moskal
doaj   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Forecasting Municipal Financial Distress in South Africa: A Machine Learning Approach

Forecasting
Persistent fiscal stress in South African municipalities undermines service delivery, yet practical tools for early detection remain limited. This study predicts one-year-ahead municipal financial distress to support risk-based prioritisation. We develop
Nkosinathi Emmanuel Radebe, Bomi Cyril Nomlala, Frank Ranganai Matenda   +2 more
doaj   +1 more source

ENHANCING FINANCIAL ACCOUNTABILITY IN SOUTH AFRICAN LOCAL MUNICIPALITIES: A CONSEQUENCE MANAGEMENT VIEWPOINT [PDF]

Financial Studies, 2022
Achieving clean audit reports has remained a difficult task for most local municipalities in South Africa due to financial misappropriation, mismanagement, and the inability to apply legal actions against the defaulters who misuse municipal financial ...
Prince Chukwuneme ENWEREJI
doaj  

Challenge of financing physical infrastructure and services in Brihanmumbai municipal corporation [PDF]

Mumbai city is a financial capital of country but at present it is facing acute pressure of rise in population and inadequate infrastructure facilities and services.
Rode, Sanjay
core