CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma +12 more
wiley +1 more source
Assessment of the Presence, Content, and Gaps in Municipal Food Service Guidelines: An Analysis of Policies in the 20 Most Populous U.S. Cities, 2017-2023. [PDF]
Oza-Frank R +5 more
europepmc +1 more source
The modulation of polar tetrahedra enabled the synthesis of an outstanding short‐wave UV NLO crystal, Zn(C2H4NO2)2[SO2(NH2)2], which achieves a rare balance of a large bandgap (5.93 eV), high birefringence (Δn = 0.126 at 546 nm), and strong SHG response (1.36 × KDP), especially achieving excellent phase‐matching throughout the full transparency range ...
Chenjie Cui +7 more
wiley +1 more source
Emissions Disclosures and Energy Use Reporting by Hospitals in the United States. [PDF]
Abel A +6 more
europepmc +1 more source
This study first extends the high‐entropy concept to I‐III‐VI quantum dots (QDs) and synthesizes CZCrGSe/ZnSe/ZnS core/shell/shell QDs with a record photoluminescence quantum yield (PLQY) of 100%. Their ZnSe/ZnS double shell efficiently passivates defects and boosts structural stability.
Maoyuan Huang +9 more
wiley +1 more source
Connection, confluence and convergence: a protocol for reviewing policies on antimicrobial resistance and plastic pollution. [PDF]
Shah-Rohlfs R +7 more
europepmc +1 more source
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong +12 more
wiley +1 more source
Territorial Constraints on Trap-Neuter-Return in Insular Landscapes: Demographic and Ecological Implications of a Conservation-Oriented Policy. [PDF]
Manzanares-Fernández R +3 more
europepmc +1 more source
A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao +14 more
wiley +1 more source
Addressing Precarious Work Through Policy and Systems Change: A Case of a Local Health Department, University, and Worker Center Collaboration in Suburban Cook County, IL. [PDF]
Jarpe-Ratner E +9 more
europepmc +1 more source

