Results 111 to 120 of about 480,840 (327)
Los Contables de la Taula de Canvis de Valencia (1519-1649). Su Formación Teórica y Práctica
Revista de Contabilidad: Spanish Accounting Review, 2000 La gestión contable de la Taula de Canvis de Valencia (siglos XVI-XVII) corría a cargo de dos notarios públicos y tres mercaderes, los cuales se responsabilizaban de la contabilidad principal y auxiliar de este Banco municipal, por lo que estos ...
Francisco Mayordomo García-Chicote
doaj
Municipal Ordinances of a Local Assembly and Their Judicial Control Measures
Public Law Journal, 2020 Sang-sik Son
semanticscholar +1 more source
Advanced Science, EarlyView.AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li +6 more
wiley +1 more source
Advanced Science, EarlyView.Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang +21 more
wiley +1 more source
Advanced Science, EarlyView.The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang +16 more
wiley +1 more source
Piscataqua Region Environmental Planning Assessment [PDF]
, 2010 The Piscataqua Region Environmental Planning Assessment (PREPA) was conducted to document the current status of environmental planning efforts and land use regulations for each of the 42 New Hampshire municipalities and 10 Maine municipalities (city and ...
Sowers, Derek
core +2 more sources
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Etnográfica: Revista do Centro em Rede de Investigação em Antropologia, 2011 Apesar de existirem posturas municipais que regulam o comércio nas ruas de Ciudad del Este (Paraguai) e de os vendedores a elas se sujeitarem - em teoria -, a forma como se ocupa o espaço para venda nas ruas revela uma série de acordos, sedimentações e ...
Fernando Rabossi
doaj
Advanced Science, EarlyView.ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source