Results 81 to 90 of about 480,840 (327)

Legal Aspects of Qualitative Municipal Noise Ordinances [PDF]

The Journal of the Acoustical Society of America, 1974
The most-favored of traditional approaches to statutory regulation of excessive noise has been the subjective or qualitative statute. We present an analysis of the legal problems of qualitative municipal noise ordinances. While such an enactment is a valid exercise of a state or municipality's police powers, a case study of the Provincetown ...
C. M. Salter, B-J. R. Jones, F. H. Brittain   +2 more
openaire   +1 more source

Assessing the Risk of 100-year Freshwater Floods in the Lamprey River Watershed of New Hampshire Resulting from Changes in Climate and Land Use [PDF]

, 2013
What is the coastal resource issue the project sought to address? Both the magnitude and frequency of freshwater flooding is on the rise in seacoast NH and around much of New England.
Miller, Steve, Peterson, Julia, Roseen, Robert, Rubin, Fay, Scholz, Ann, Simpson, Michael, Sinnott, Cliff, Townson, Lisa, Wake, Cameron P.   +8 more
core   +4 more sources

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

El paisaje pesquero de Jerez de la Frontera a finales de la Edad Media: caladeros, flota, distribución y consumo

Historia. Instituciones. Documentos, 2018
Jerez de la Frontera was not one of the fishing powers of the Late medieval andalusian coast. their relative distance from the atlantic coast, a whole series of jurisdictional disputes with the seigniories of the area, and the preponderance of other ...
Enrique José Ruiz Pilares
doaj   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

Evaluation of Loading and Unloading Zones Through Dynamic Occupancy Scenario Simulation Aligned with Municipal Ordinances in Urban Freight Distribution

Applied Sciences
This study analyses the operational efficiency of urban loading and unloading zones (LUZs) by applying queuing theory without waiting (Erlang B model) and incorporating weighted occupancy time as a fundamental metric.
Angel Gil Gallego, María Pilar Lambán Castillo, Jesús Royo Sánchez, Juan Carlos Sánchez Catalán, Paula Morella Avinzano   +4 more
doaj   +1 more source

Addressing Small Scale Fisheries Management through Participatory Action Research (PAR), an Experience from the Philippines

International Journal of Agriculture System, 2015
This case demonstrates the potential of addressing small scale fisheries management through participatory action research (PAR) in one of the CRP 1.3/AAS sites in the Philippines.
Lutgarda L. Tolentino, Lily Ann D. Lando, Len R. Garces, Maripaz L. Perez, Claudia B. Binondo, Jane Marina Apgar   +5 more
doaj   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Classification of cases of animal abuse in Ecuador using IndetermSoft and C4.5 algorithms [PDF]

Neutrosophic Sets and Systems
This dissertation aimed to determine the classification of animal abuse within Ecuador by severity, con text, and solution through the application of IndetermSoft and the statistical-neutrosophic C4.5 algorithm to classify the uncertainty associated with
Viviana del Rocío Marfetan Marfetan, Lesly Gissela Tipanguano Chicaiza, Styven Andrés Pila Chicaiza, Estephany Monserrath Ojeda Sanchez   +3 more
doaj   +1 more source