Results 101 to 110 of about 366,908 (315)

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Information in connection with the Municipality of Stellenbosch no. 45, 1949-08

open access: yes, 1949
ims_1949-08.pdf derived from archival TIFF file. Digital copies were created from the original hard copy collection of the newsletter held by Stellenbosch Library and Information Service Africana Collection.IMS (Information in connection with the ...

core  

Overcoming the Trade‐Off Between Magnetic Coupling and Electrical Insulation in Soft Magnetic Materials via Nanochain Engineering

open access: yesAdvanced Science, EarlyView.
This study employs a nanochain engineering approach combined with an in situ oxidation strategy to fabricate self‐insulating iron‐based magnetic nanochains, addressing the challenge of balancing magnetic coupling and electrical insulation in soft magnetic materials.
Dingrong Zuo   +8 more
wiley   +1 more source

Non-cash food assistance and household food security: Evidence from remote Indonesia

open access: yesEconomic Journal of Emerging Markets
Purpose ― This study aims to evaluate the impact of Indonesia’s Non-Cash Food Assistance Program (BPNT) on household consumption and food security in Sabu Raijua, a remote region in Indonesia with limited food access.
Rizki Tri Anggara   +1 more
doaj   +1 more source

Information in connection with the Municipality of Stellenbosch 1956-08

open access: yes, 1956
ims_1956-08.pdf derived from archival TIFF file. Digital copies were created from the original hard copy collection of the newsletter held by Stellenbosch Library and Information Service Africana Collection.IMS (Information in connection with the ...

core  

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

open access: yesAdvanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang   +7 more
wiley   +1 more source

Project MOVE HEALTHY

open access: yesBaltic Journal of Sport and Health Sciences
The free training project MOVE HEALTHY, which started in Kaunas in 2013, was initiated by members of the public, and was later taken over by the Kaunas City Municipality, together with the city’s Public Health Bureau. The idea behind the project was to
Laura Motužytė, Gerda Kuzmarskienė
doaj   +1 more source

L’apolitisme municipal [PDF]

open access: yesBulletin d'histoire politique, 2012
Bherer, Laurence, Breux, Sandra
openaire   +4 more sources

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

Genomic surveillance of Canadian airport wastewater samples allows early detection of emerging SARS-CoV-2 lineages

open access: yesScientific Reports
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has shown wastewater (WW) surveillance to be an effective means of tracking the emergence of viral lineages which arrive by many routes of transmission including via transportation
Alyssa K. Overton   +35 more
doaj   +1 more source

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