Results 1 to 10 of about 20,649 (250)

Chronicity of high and low level mupirocin resistance in Staphylococcus aureus from 30 Indian hospitals

Scientific Reports, 2023
Mupirocin is one of the most effective topically used antibiotic for the treatment of dermatitis, nasal carriage, decolonization of methicillin susceptible Staphylococcus aureus and eradication of methicillin resistant Staphylococcus aureus.
Rajni Prakash, Amar Garg, Riteshkumar Arya, R. K. Kumawat   +3 more
doaj   +2 more sources

Development and characterization of mupirocin encapsulated in animal bone-derived hydroxyapatite for management of chronic wounds

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background Hydroxyapatite is an important biomedical material used in drug delivery owing to its excellent bioactivity and biocompatibility. In this study, hydroxyapatite isolated from bovine and caprine bones was capped and used as a drug carrier to ...
Olusola Emmanuel Ojo, Margaret Okonawan Ilomuanya, Olatunde Israel Sekunowo, Oluwashina Philips Gbenebor, Samson Oluropo Adeosun   +4 more
doaj   +2 more sources

Mupirocin Promotes Wound Healing by Stimulating Growth Factor Production and Proliferation of Human Keratinocytes

Frontiers in Pharmacology, 2022
Mupirocin has been reported for its role in the treatment of infected wounds through its antibacterial activity, however the role of mupirocin in promoting wound healing via alternative mechanisms has not been extensively evaluated.
Danielle Twilley, Oleg Reva, Debra Meyer, Namrita Lall, Namrita Lall, Namrita Lall, Namrita Lall   +6 more
doaj   +2 more sources

The impact of hospital wide measures to reduce mupirocin resistance among methicillin-resistant Staphylococcus aureus in a Singapore hospital [PDF]

Antimicrobial Stewardship & Healthcare Epidemiology
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of healthcare associated infections. Colonization with MRSA increases the risk of subsequent nosocomial infection.
HML Oh, J Chen
doaj   +5 more sources

Dissemination of Methicillin-Resistant Staphylococcus aureus Sequence Type 764 Isolates with Mupirocin Resistance in China

Microbiology Spectrum, 2023
Mupirocin, a topical antimicrobial agent, is an important component in the eradication of methicillin-resistant Staphylococcus aureus (MRSA) colonization.
Yinjuan Guo, Linling Xu, Bingjie Wang, Lulin Rao, Yanlei Xu, Xinyi Wang, Huilin Zhao, Jingyi Yu, Ying Zhou, Fangyou Yu   +9 more
doaj   +2 more sources

Mupirocin Resistance [PDF]

Clinical Infectious Diseases, 2009
With increasing pressure to prevent methicillin-resistant Staphylococcus aureus (MRSA) infection, it is possible that there will be increased use of mupirocin for nasal decolonization of MRSA. Understanding the mechanisms, clinical significance, and epidemiology of mupirocin resistance is important for predicting how changes in mupirocin use may affect
Jean B, Patel, Rachel J, Gorwitz, John A, Jernigan   +2 more
exaly   +3 more sources

Therapeutic Potential of Injectable Nano-Mupirocin Liposomes for Infections Involving Multidrug-Resistant Bacteria

Pharmaceutics, 2021
Antibiotic resistance is a global health threat. There are a few antibiotics under development, and even fewer with new modes of action and no cross-resistance to established antibiotics.
Ahuva Cern, Yaelle Bavli, Atara Hod, Daniel Zilbersheid, Shazad Mushtaq, Ayelet Michael-Gayego, Dinorah Barasch, Yael Feinstein Rotkopf, Allon E. Moses, David M. Livermore, Yechezkel Barenholz   +10 more
doaj   +2 more sources

Formulation by Design of an Innovative Tea Tree Oil Nanoemulgel Incorporating Mupirocin for Enhanced Wound Healing Activity

Applied Sciences, 2023
Mupirocin is an antibacterial agent that has been documented to be effective in treating superficial skin infections. However, the main limitation of its application is bacterial resistance. Therefore, there is a need to determine a way to potentiate its
Mahdi M. Bujubarah, Heba S. Elsewedy, Tamer M. Shehata, Wafaa E. Soliman   +3 more
doaj   +2 more sources

Mupirocin resistance in Staphylococcus aureus: A systematic review and meta-analysis

Journal of Global Antimicrobial Resistance, 2020
BACKGROUND AND AIM Staphylococcus aureus (S. aureus) is one of the most common pathogens causing nosocomial and community-acquired infections which associate with high morbidity and mortality rates. Mupirocin has been increasingly used for treatment of S.
Masoud Dadashi, Bahareh Hajikhani, Davood Darban-Sarokhalil   +2 more
exaly   +2 more sources

Exploiting Broad-Spectrum Chimeric Lysin to Cooperate with Mupirocin against Staphylococcus aureus-Induced Skin Infections and Delay the Development of Mupirocin Resistance

Microbiology Spectrum, 2023
Staphylococcus aureus often leads to severe skin infections. However, S. aureus is facing a crisis of antibiotic resistance. The combination of phage and antibiotics is effective for drug-resistant S. aureus infections.
Xiao-chao Duan, Xin-xin Li, Xiang-min Li, Shuang Wang, Fen-qiang Zhang, Ping Qian   +5 more
doaj   +2 more sources