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The impact of hospital wide measures to reduce mupirocin resistance among methicillin-resistant Staphylococcus aureus in a Singapore hospital [PDF]
Antimicrobial Stewardship & Healthcare EpidemiologyIntroduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of healthcare associated infections. Colonization with MRSA increases the risk of subsequent nosocomial infection.
HML Oh, J Chen
doaj +5 more sources
Frontiers in Pharmacology, 2022 Mupirocin has been reported for its role in the treatment of infected wounds through its antibacterial activity, however the role of mupirocin in promoting wound healing via alternative mechanisms has not been extensively evaluated.
Danielle Twilley +2 more
exaly +3 more sources
Synergistic activity of mupirocin in combination with protocatechuic acid ethyl ester against mupirocin-resistant MRSA [PDF]
Frontiers in Cellular and Infection MicrobiologyThe prevalence of mupirocin resistance in MRSA severely limits therapeutic options for skin and soft tissue infections. This study aimed to evaluate the potential synergistic activity between mupirocin and protocatechuic acid ethyl ester (EDHB) through ...
Li Shen +11 more
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In Vitro Activity of Mupirocin Against Methicillin-Resistant Staphylococcus aureus (MRSA) in Two Periods of Time (2016 and 2021–2022) in a Large University Hospital in Germany [PDF]
MicroorganismsColonization with methicillin-resistant Staphylococcus aureus (MRSA) increases the risk of adverse health outcomes, and it is estimated that 10–30% of carriers subsequently develop infection. Mupirocin is currently widely used as a topical decolonization
Arved Carl Christian Westphal +2 more
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Molecules, 2019 Because of the bacterial drug resistance development, it is reasonable to investigate chemical compounds capable of preventing the spread of resistance to mupirocin (MUP), commonly used in staphylococcal eradication.
Pawel Kwiatkowski +2 more
exaly +3 more sources
Clinical Infectious Diseases, 2009 With increasing pressure to prevent methicillin-resistant Staphylococcus aureus (MRSA) infection, it is possible that there will be increased use of mupirocin for nasal decolonization of MRSA. Understanding the mechanisms, clinical significance, and epidemiology of mupirocin resistance is important for predicting how changes in mupirocin use may affect
Jean B, Patel +2 more
openaire +2 more sources
Asian Journal of Medical Sciences, 2023 Background: Skin and soft-tissue infections (SSI) caused by Staphylococcus aureus remain a significant concern in both community and hospital settings.
Karuna Ahire +3 more
doaj +1 more source
Pharmaceutics, 2021 Antibiotic resistance is a global health threat. There are a few antibiotics under development, and even fewer with new modes of action and no cross-resistance to established antibiotics.
Ahuva Cern +10 more
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Beni-Suef University Journal of Basic and Applied Sciences, 2022 Background Hydroxyapatite is an important biomedical material used in drug delivery owing to its excellent bioactivity and biocompatibility. In this study, hydroxyapatite isolated from bovine and caprine bones was capped and used as a drug carrier to ...
Olusola Emmanuel Ojo +4 more
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Screening for Mupirocin Resistance in Staphylococcus [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: Mupirocin is widely used topical antibiotic for the treatment of skin and soft tissue infections caused by Staphylococcus and Streptococcus.
AVR JEYA SANJU +2 more
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