Results 201 to 210 of about 20,649 (250)
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Exploring mechanisms of mupirocin resistance and hyper-resistance.
Biochemical Society TransactionsMupirocin is a broad-spectrum antibiotic that acts predominantly against Gram-positive bacteria. It is produced by Pseudomonas fluorescens NCIMB 10586 and has been clinically used to treat primary and secondary skin infections and to eradicate nasal ...
Igor Živković, I. Gruic‐Sovulj
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Failure of mupirocin-resistant staphylococci to inactivate mupirocin
European Journal of Clinical Microbiology & Infectious Diseases, 1989Isolates from four UK centres, comprising four Staphylococcus aureus strains and one Staphylococcus epidermidis strain with high-level mupirocin resistance, and one strain each of Staphylococcus aureus and Staphylococcus epidermidis with low-level mupirocin resistance, were assessed for intracellular or extracellular enzymatic alteration of the ...
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Mupirocin resistance is not an inevitable consequence of mupirocin use
Journal of Hospital Infection, 2011The rate of mupirocin resistance in meticillin-resistant Staphylococcus aureus (MRSA) in Besançon University Hospital is low with a decreasing trend, from 10% in 2004 to 3% in 2009. This trend in resistance paralleled mupirocin consumption. Genotyping results showed that this decrease was not linked to a change in MRSA clones.
Talon, D. +3 more
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Nano-mupirocin: enabling the parenteral activity of mupirocin
European Journal of Nanomedicine, 2016Abstract Mupirocin is an antibiotic having a unique mode of action, not shared by any other therapeutically available antibiotic. However, due to its rapid elimination following injection and high protein binding, current therapeutic use is limited to topical administration.
Ahuva Cern +7 more
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Mupirocin-Resistant, Methicillin-ResistantStaphylococcus aureus: Does Mupirocin Remain Effective?
Infection Control & Hospital Epidemiology, 2003AbstractObjective:To determine the efficacy of mupirocin ointment in reducing nasal colonization with mupirocin-susceptible, methicillin-resistantStaphylococcus aureus(MS MRSA) as well as mupirocin-resistant MRSA (MR MRSA).Design:Prospective evaluation in which patients colonized with MRSA were treated twice daily with 2% topical mupirocin ointment for
Walker, Elaine S. +4 more
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Microbial Drug Resistance, 2019
Aim: The aim of this study was to evaluate the effect of subinhibitory concentrations of trans-anethole on antibacterial and antibiofilm properties of mupirocin against mupirocin-resistant Staphylococcus aureus strains. Methods: Following parameters were
P. Kwiatkowski +7 more
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Aim: The aim of this study was to evaluate the effect of subinhibitory concentrations of trans-anethole on antibacterial and antibiofilm properties of mupirocin against mupirocin-resistant Staphylococcus aureus strains. Methods: Following parameters were
P. Kwiatkowski +7 more
semanticscholar +1 more source
2017
Mupirocin, formerly called pseudomonic acid A, is a naturally occurring antibiotic that was originally isolated as a fermentation product from Pseudomonas fluorescens. It binds reversibly to the bacterial isoleucyl transfer-RNA synthetase and thereby inhibits bacterial protein and RNA synthesis, ultimately leading to bacterial death (Poovelikunnel et ...
Verkaik, Nelianne J., Vos, Margreet C.
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Mupirocin, formerly called pseudomonic acid A, is a naturally occurring antibiotic that was originally isolated as a fermentation product from Pseudomonas fluorescens. It binds reversibly to the bacterial isoleucyl transfer-RNA synthetase and thereby inhibits bacterial protein and RNA synthesis, ultimately leading to bacterial death (Poovelikunnel et ...
Verkaik, Nelianne J., Vos, Margreet C.
openaire +1 more source