Results 151 to 160 of about 649 (244)
Advanced Science, Volume 13, Issue 46, 17 August 2026.SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao +15 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Mechanical thrombectomy can provide rapid, fibrinolysis‐free restoration of venous flow in phlegmasia cerulea dolens. This case highlights an unusually severe course with extensive iliofemorocaval thrombosis, rhabdomyolysis, MRI‐confirmed muscle necrosis, and arterial hypoperfusion despite anticoagulation, in which urgent intervention achieved
Johan Filo +4 more
wiley +1 more source
Severe Ulcerative Colitis With Cytomegalovirus Colitis Treated by Early Surgery: A Case Report
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Acute severe ulcerative colitis complicated by cytomegalovirus infection requires individualized management, and timely surgical intervention should be considered in carefully selected high‐risk patients who are unlikely to benefit from further medical therapy.
Hiroyuki Fujimura +4 more
wiley +1 more source
Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases
Comprehensive Physiology, Volume 16, Issue 4, August 2026.Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal +2 more
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.Gambogic acid exerts anticancer effects through reactive oxygen species‐mediated apoptosis, suppression of nuclear factor kappa B and phosphatidylinositol‐3‐kinase–protein kinase B signalling, multidrug resistance modulation and tumour microenvironment effects.
Uttam Singh Baghel +14 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.• ADAMTS4 is induced primarily in cardiac fibroblasts during sepsis. • ADAMTS4 cleaves TSP1 at the 236–246 aa functional region. • TSP1 cleavage activates TGF‐β/Smad and NF‐κB signalling in fibroblasts. • Targeting ADAMTS4 reduces fibroblast activation and cardiac fibrosis.
Zhe‐Wei Zhang +12 more
wiley +1 more source
Hodgkin lymphoma of the ampulla of Vater: A rare cause of obstructive jaundice in children
JPGN Reports, Volume 7, Issue 3, Page 398-402, August 2026.Abstract Hodgkin lymphoma (HL) has a wide spectrum of presentation. Most cases affect lymph nodes (nodal), while extranodal involvement is rare. Whereas the gastrointestinal tract is enriched with lymphoid tissues, the ampulla of Vater is not rich in lymphoid tissue. Involvement of the ampulla of Vater with HL has rarely been reported in adults and has
Sultana Alshammari +12 more
wiley +1 more source
Lymphatic Endothelial Cells in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang +5 more
wiley +1 more source
Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions
MedComm, Volume 7, Issue 8, August 2026.This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei +9 more
wiley +1 more source
Optometry and Vision Science, Volume 103, Issue 8, August 2026.ABSTRACT Purpose To highlight retinal ischemia as an important component of diabetic retinopathy (DR) pathogenesis, a significant prognostic factor, and a driver of various DR complications, including neovascularization. We aim to describe the main features of ischemic areas that can be identified through fundoscopy, color fundus photography, optical ...
Marina Guro +6 more
wiley +1 more source