Results 151 to 160 of about 230 (222)

Advancing gambogic acid for translational oncology: Redox–proteostasis collapse, multidrug resistance reversal, nanodelivery and biomarker‐guided development

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Gambogic acid exerts anticancer effects through reactive oxygen species‐mediated apoptosis, suppression of nuclear factor kappa B and phosphatidylinositol‐3‐kinase–protein kinase B signalling, multidrug resistance modulation and tumour microenvironment effects.
Uttam Singh Baghel, Kajal Gurow, Geetanjali Mehara, Priyanka Kriplani, Neelam M. Patel, Abhay Sharma, Deeksha Singh, Atamjit Singh, Suchi Dave, Bhawani Singh, Lashyn N. Kiyekbayeva, William N. Setzer, Javad Sharifi‐Rad, Cheryl Grace Pratiwi Rumahorbo, Daniela Calina   +14 more
wiley   +1 more source

ADAMTS4 mediates LPS‐induced cardiac injury and myocardial fibrosis through proteolytic cleavage of TSP1

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
• ADAMTS4 is induced primarily in cardiac fibroblasts during sepsis. • ADAMTS4 cleaves TSP1 at the 236–246 aa functional region. • TSP1 cleavage activates TGF‐β/Smad and NF‐κB signalling in fibroblasts. • Targeting ADAMTS4 reduces fibroblast activation and cardiac fibrosis.
Zhe‐Wei Zhang, Shi‐Yan Wan, Wen Li, Xiao Lu, Rong Chen, Xin Xing, Wei Lai, Shu‐Yang Sheng, M. M. Mosebetsi, Qing‐Tao Meng, Zi‐Long Lu, Di Fan, Wan‐Li Jiang   +12 more
wiley   +1 more source

Hodgkin lymphoma of the ampulla of Vater: A rare cause of obstructive jaundice in children

JPGN Reports, Volume 7, Issue 3, Page 398-402, August 2026.
Abstract Hodgkin lymphoma (HL) has a wide spectrum of presentation. Most cases affect lymph nodes (nodal), while extranodal involvement is rare. Whereas the gastrointestinal tract is enriched with lymphoid tissues, the ampulla of Vater is not rich in lymphoid tissue. Involvement of the ampulla of Vater with HL has rarely been reported in adults and has
Sultana Alshammari, Homoud Alhebbi, Awad Al Qahtani, Sarah Algubaisi, Faisal Alhaffaf, Abdulrahman Al Robayan, Mohammed Almutairi, Saeed Alshieban, Mohammad Alshahrani, Tarek Khaled Alfawzan, Khalid Alkhamis, Ibrahim Al Hasan, Sami Wali   +12 more
wiley   +1 more source

Lymphatic Endothelial Cells in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang, Wang Lin, Hengyang Liu, Jixin Zhong, Shiliang Li, Xiaoquan Rao   +5 more
wiley   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Case series: The role of retinal ischemia in the pathogenesis and clinical manifestation of diabetic retinopathy

Optometry and Vision Science, Volume 103, Issue 8, August 2026.
ABSTRACT Purpose To highlight retinal ischemia as an important component of diabetic retinopathy (DR) pathogenesis, a significant prognostic factor, and a driver of various DR complications, including neovascularization. We aim to describe the main features of ischemic areas that can be identified through fundoscopy, color fundus photography, optical ...
Marina Guro, Henrietta Wang, Jack Phu, Kaitlyn A. Sapoznik, Hamza Shah, Maggie L. Zhang, Michael Kalloniatis   +6 more
wiley   +1 more source

Uncovering new insights through young children's voices: A qualitative research meta‐synthesis on practicing mindfulness at school

Review of Education, Volume 14, Issue 2, August 2026.
Abstract The intention guiding the design of this study was to amplify and listen to children's voices in early years research. The aim of this qualitative research meta‐synthesis was to engage in new analyses and interpretations about mindfulness through the lens of young children.
Elizabeth Joy Erwin, Mia J. Palombo, Meredith Valentine, Laura Adair Clark   +3 more
wiley   +1 more source

Of cables and threads

American Ethnologist, Volume 53, Issue 3, Page 283-295, August 2026.
Abstract Over the past two decades, gondola lifts have become central to interventions in urban Latin America's auto‐constructed peripheries. As cable car urbanism reshapes the city's edge, it raises fundamental questions about the notion of the “urban fabric” as a sociomaterial practice, an epistemology, and a site of politics.
Federico Pérez Fernández
wiley   +1 more source

Computed tomography findings of peritoneal tumour in the absence of primary lesions: preliminary study

Australian Veterinary Journal, Volume 104, Issue 8, Page 532-537, August 2026.
Primary peritoneal tumours are uncommon and include mesothelioma and carcinoma. Mesothelioma identification is challenging, as there are no established rapid diagnostic methods. In the absence of a simple means of diagnosis, evaluation often requires several invasive biopsies, highlighting the need to develop a definitive diagnostic method.
T Tanaka, M Tomihari, T Hasegawa
wiley   +1 more source