Results 31 to 40 of about 972 (251)
Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
Advanced Science, EarlyView.This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
wiley +1 more source
American Indian Graffiti Muralism: Survivance and Geosemiotic Signposts in the American Cityscape
, 2016 American Indian graffiti muralism is a terminology that embodies the contemporary public art form of mural production by American Indian artists using public art installations to express ontologies of sovereignty, self-determination, and identity in ...
Healey, Gavin A.
core +3 more sources
TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains
Advanced Science, EarlyView.Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang +14 more
wiley +1 more source
Advanced Science, EarlyView.Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin +7 more
wiley +1 more source
Primary mural endocarditis [PDF]
European Heart Journal, 2007 A 57-year-old male was admitted with a 2-week history of fever, rigours, and confusion and a single episode of retrosternal chest pain. He had recently undergone a circumcision. Clinical examination revealed a temperature of 38.3°C and a balanitis. Urinanalysis revealed haematuria and proteinuria.
Peadar F, McKeown +2 more
openaire +2 more sources
Advanced Science, EarlyView.Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han +11 more
wiley +1 more source
International Arte Popular: Mexican, American, and French Muralism 1920‒1940
, 2023 This dissertation tracks the Mexican government’s intentional export of muralism and the subsequent adoption of the movement’s strategies in the United States and France during the 1920s and 1930s.
Fernandez-Barkan, Davida
core +2 more sources
AmerikaThis work analyzes Annette Nancarrow's mural, A Boy's Dream of Becoming a Bullfighter (1949), based on her biography and a study of its iconographic program. The stylistic features of the work are examined, along with the artist's memoirs and testimonies.
Dina Comisarenco Mirkin
doaj +1 more source
Advanced Science, EarlyView.Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu +14 more
wiley +1 more source
The Mexican Walls: A Challenge for the Female Spanish Exiled Artists
Investigaciones Feministas, 2018 This paper focuses on the muralism of the female Spanish artists exiled in Mexico after the Spanish Civil War. Although we are studying some specific artists, the murals which we explain here –some of them unknown until now– show the female refugees ...
Carmen Gaitan Salinas
doaj +1 more source