Ribosome profiling of the retrovirus murine leukemia virus [PDF]
Retrovirology, 2018 Background The retrovirus murine leukemia virus (MuLV) has an 8.3 kb RNA genome with a simple 5′-gag-pol-env-3′ architecture. Translation of the pol gene is dependent upon readthrough of the gag UAG stop codon; whereas the env gene is translated from ...
Nerea Irigoyen +3 more
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ESCRT Requirements for Murine Leukemia Virus Release [PDF]
Viruses, 2016 The Murine Leukemia Virus (MLV) is a gammaretrovirus that hijack host components of the endosomal sorting complex required for transport (ESCRT) for budding.
Christina Bartusch, Reinhild Prange
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Murine leukemia virus (MLV) P50 protein induces cell transformation via transcriptional regulatory function [PDF]
Retrovirology, 2023 Background The murine leukemia virus (MLV) has been a powerful model of pathogenesis for the discovery of genes involved in cancer. Its splice donor (SD’)-associated retroelement (SDARE) is important for infectivity and tumorigenesis, but the mechanism ...
Charbel Akkawi +7 more
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Structure and Leukemogenic Activity of a Murine Leukemia Virus [PDF]
Journal of Virology, 1968 Purified Friend viruses obtained from chronically infected tissue cultures were studied under the electron microscope in an effort to correlate the fine structure of the particles to their leukemogenic activity under varied experimental conditions, i.e., temperature treatments and exposure to Tween 80, amyl acetate, or ether.
L. de Tkaczevski +2 more
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Essential functions of inositol hexakisphosphate (IP6) in murine leukemia virus replication [PDF]
mBioWe have investigated the function of inositol hexakisphosphate (IP6) and inositol pentakisphosphate (IP5) in the replication of murine leukemia virus (MLV).
Banhi Biswas +7 more
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BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis [PDF]
Microbiology Spectrum, 2022 Moloney murine leukemia virus (MLV) infects BALB/c mice and induces T-cell lymphoma in mice. Retroviral integration is mediated by the interaction of the MLV integrase (IN) with members of the bromodomain and extraterminal motif (BET) protein family ...
Ivan Nombela +12 more
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Immunofluorescent Antibody Studies of a Murine Leukemia Virus [PDF]
Journal of Bacteriology, 1966 Brown, Eric R. (Northwestern University Medical School, Chicago, Ill.), Peter Buinauskas, and Steven O. Schwartz . Immunofluorescent antibody studies of a murine leukemia virus. J. Bacteriol. 92: 978–982.
Eric Brown +2 more
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Analysis of the Ribonucleic Acid of Murine Leukemia Virus [PDF]
Journal of Virology, 1969 Cells producing the Rauscher strain of murine leukemia virus (MLV) were exposed to 3 H-uridine, and labeled virus was collected at hourly intervals. Ribonucleic acid (RNA) extracted from virions (vRNA) had a characteristic single peak when analyzed by electrophoresis in polyacrylamide-agarose composite gels ...
John P. Bader, Theodore L. Steck
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Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus [PDF]
Nature Communications, 2016 Retroviral reverse transcriptase from Moloney Murine Leukemia Virus (MoMLV) requires interaction with peptidyl release factor 1. Here, the authors report the crystal structure of this complex, and provide insights into how MoMLV uses the host translation
Xuhua Tang +8 more
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Phosphorylation Requirement of Murine Leukemia Virus p12. [PDF]
J Virol, 2016 ABSTRACT The p12 protein of murine leukemia virus (MLV) Gag is associated with the preintegration complex (PIC), and mutants of p12 (PM14) exhibit defects in nuclear entry/retention. Mutants of the phosphorylated serine 61 also have been reported to have defects in the early life cycle.
Brzezinski JD +4 more
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