Results 91 to 100 of about 97,240 (266)

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

Interferon-gamma: A Potent Antiviral Agent Targeting Macrophages Infected with LP-BM5 Murine Leukemia Virus, the Causative Agent of 'AIDS' in Mice

open access: yesCanadian Journal of Infectious Diseases, 1992
Cells of the monocyte/macrophage lineage (MM cells) are known to be infected by retroviruses, including the human immunodeficiency virus (HIV), without cytopathic changes and may serve as a persistent reservoir for the virus during the development of ...
Jens J Kort, Julie L Eiseman
doaj   +1 more source

Structure and Leukemogenic Activity of a Murine Leukemia Virus [PDF]

open access: bronze, 1968
L. de Tkaczevski   +2 more
openalex   +1 more source

Computational Characterization of the Role of LEM2/LaminA Interactions on the Stability of BAF‐Dimer Using Molecular Simulations

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The effect of the presence of the BAF‐binding LEM‐domain and LaminA Ig‐fold on the stability of the BAF dimer was studied qualitatively using non‐equilibrium pull simulations and quantitatively through the calculation of the potential of mean force profile along BAF–BAF separation distance.
Aswin Vinod Muthachikavil   +2 more
wiley   +1 more source

Animal models on HTLV-1 and related viruses: what did we learn?

open access: yesFrontiers in Microbiology, 2012
Oncoviridae regroup several related retroviruses such as Human T-cell lymphotropic viruses (HTLV), Simian T cell lymphotropic viruses (STLV), and Bovine leukemia virus (BLV).
Hiba Ahmad El Hajj   +8 more
doaj   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

Xenotropic murine leukemia virus-related virus is susceptible to AZT

open access: yesVirology, 2010
The xenotropic murine leukemia virus-related virus (XMRV) is a human retrovirus, recently isolated from tissues of prostate cancer patients with impaired RNase L activity. In this study, we evaluated 10 licensed anti-HIV-1 compounds for their activity against XMRV, including protease inhibitors (PI), nucleoside reverse transcriptase (RT) inhibitors ...
Sakuma, Ryuta   +4 more
openaire   +2 more sources

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

open access: yesSmall Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke   +3 more
wiley   +1 more source

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