Results 121 to 130 of about 72,711 (261)

Effects of Fuzheng Paidu tablet immunization on AIDS BALB/c mice

open access: yesSaudi Pharmaceutical Journal, 2017
Aim: To establish a Friend murine leukemia virus (FLV)-induced immunodeficient BALB/C mouse model and investigate the effects of Fuzheng Paidu tablets on the body weight, thymus, spleen, and CD4+ and CD8+ T lymphocytes of FLV-infected mice.
Mingsan Miao   +6 more
doaj  

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

open access: yesNeuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal   +2 more
wiley   +1 more source

Analysis of IDH1 and IDH2 mutations as causes of the hypermethylator phenotype in colorectal cancer

open access: yesThe Journal of Pathology, EarlyView.
Abstract The CpG island methylator phenotype (CIMP) occurs in many colorectal cancers (CRCs). CIMP is closely associated with global hypermethylation and tends to occur in proximal tumours with microsatellite instability (MSI), but its origins have been obscure.
Joseph C Ward   +59 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

Augmented 3D Printing for Multiscale Microphysiological Systems

open access: yesSmall, EarlyView.
This review explores augmented 3D printing techniques combined with multiscale ancillary methods to overcome current limitations in fabricating complex microphysiological systems (MPS). It covers 3D printing and ancillary techniques, and highlights advancements in augmented MPS that surpass conventional systems, offering more physiologically relevant ...
Kyeong Seob Hwang   +7 more
wiley   +1 more source

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