Results 141 to 150 of about 72,711 (261)
CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma+6 more
wiley +1 more source
Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses [PDF]
Yueh‐hsiu Chien+4 more
openalex +1 more source
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie+9 more
wiley +1 more source
SARS-CoV-2 Spike S2 Refolding: Structural Insights and Inhibition Strategies Against Emerging Variants. [PDF]
MedComm, Volume 6, Issue 8, August 2025.
Xu C, Xie W, Long X.
europepmc +2 more sources
G(AKSL2): a new cell surface antigen of the mouse related to the dualtropic mink cell focus-inducing class of murine leukemia virus detected by naturally occurring antibody. [PDF]
Elisabeth Stockert+4 more
openalex +1 more source
Clonal Hematopoiesis and Solid Cancers
This review explores the relationship between clonal hematopoiesis and solid cancers. Clonal hematopoiesis mutations influence the tumor microenvironment by altering immune regulation, inflammation, and angiogenesis. Understanding these mutations has important clinical implications, including their role in prognosis, treatment response, and potential ...
Yen T. M. Nguyen+3 more
wiley +1 more source
Characterization of the type and group specificities of the immune response in mice to murine leukemia viruses [PDF]
James N. Ihle+2 more
openalex +1 more source
The Role of Histone Methyltransferase SETDB1 in Normal and Malignant Hematopoiesis
In this review, we discuss the role of SETDB1 in gene regulation, including an overview of its structural features and key cofactors. We also highlight the lineage‐specific roles of SETDB1 in both normal hematopoietic processes and hematological malignancies, emphasizing its function as an immune checkpoint molecule that suppresses natural killer cell ...
Yu‐Hsuan Chang, Susumu Goyama
wiley +1 more source