Results 151 to 160 of about 97,240 (266)

Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an overview of the therapeutic GPCR‐antibody target landscape and examines the diversity ...
Catherine J. Hutchings, Serbülent Ünsal, Mathieu Rappas, Matthew Barnes, Maria Waldhoer, Ben Holland, Martin Culka   +6 more
wiley   +1 more source

In Vivo Footprinting of the Enhancer Sequences in the Upstream Long Terminal Repeat of Moloney Murine Leukemia Virus: Differential Binding of Nuclear Factors in Different Cell Types [PDF]

, 1998
Steven W. Granger, Hung Fan
openalex   +1 more source

T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Hepatocellular carcinoma (HCC), accounting for over 90% of primary liver cancers, remains a major global challenge for healthcare professionals. While immunotherapy has transformed the landscape of cancer treatment, its success is often limited by immune resistance, particularly through T cell exhaustion which remains a major barrier to ...
Kosar Nouri, Negar Asadollahei, Yasamin Haghir‐Sharif‐Zamini, Homeyra Seydi, Mahsa Salehi, Mehrnaz Mesdaghi, Mustapha Najimi, Massoud Vosough   +7 more
wiley   +1 more source

Stability of AML1 (core) site enhancer mutations in T lymphomas induced by attenuated SL3-3 murine leukemia virus mutants [PDF]

, 1997
H W Amtoft, Annette Balle Sørensen, Corinne Bareil, Jennie Spicker Schmidt, A. Luz, Finn Skou Pedersen   +5 more
openalex   +1 more source

Exosomal HMGB1 Orchestrates NSCLC Progression and Immunosuppressive Macrophage Polarisation Through the TLR4/NF‐κB/IL‐6/STAT3 Signalling Cascade

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT High mobility group box 1 (HMGB1), a prototypical alarmin and chromatin‐binding protein, has emerged as a critical mediator of tumour‐associated inflammation and immune regulation. Although its soluble form has been implicated in various malignancies, the functional contribution of HMGB1 encapsulated within exosomes remains incompletely ...
Jia‐Ru Huang, Wen‐Chao Gu, Ya‐Ping Yuan, Jun‐Xia Yang, Yan Chen, Xiao‐Xia Guo, Wei Ding   +6 more
wiley   +1 more source

Intact Viral Particle Counts Measured by Flow Virometry Provide Insight into the Infectivity and Genome Packaging Efficiency of Moloney Murine Leukemia Virus. [PDF]

J Virol, 2020
Renner TM, Tang VA, Burger D, Langlois MA.   +3 more
europepmc   +1 more source

Pseudotype Formation of Moloney Murine Leukemia Virus with Sendai Virus Glycoprotein F [PDF]

, 1998
Martin Spiegel, Michael Bitzer, Andrea Schenk, Heidi Rossmann, Wolfgang J. Neubert, Ursula Seidler, Michael Gregor, Ulrich M. Lauer   +7 more
openalex   +1 more source

Fifty Years of Natural Killer Cells: Milestones and Future Horizons

Scandinavian Journal of Immunology, Volume 103, Issue 2, February 2026.
To mark 50 years of NK cell research, a 2025 Karolinska symposium traced discoveries from spontaneous cytotoxicity and “missing self” recognition to receptor biology, cellular diversity, and translational advances, highlighting NK cells’ evolution into modern immunotherapy.
Andreas Lundqvist, Arnika K. Wagner, Benedict J. Chambers, Carin I. M. Dahlberg, Jonas Sundbäck, Angelica Cuapio, Evren Alici, Hans‐Gustaf Ljunggren   +7 more
wiley   +1 more source

Plasmon-enhanced photocatalytic nanoreactors for selective inactivation of murine leukemia virus (MLV). [PDF]

Nanoscale Adv
Ouyang T, Kundu K, Hood J, Cheng B, Mei Y, Gray A, Gummuluru S, Reinhard BM.   +7 more
europepmc   +1 more source

A Small Loop in the Capsid Protein of Moloney Murine Leukemia Virus Controls Assembly of Spherical Cores

, 2006
Marcy R. Auerbach, Kristy Brown, Artem Kaplan, Denise de Las Nueces, Ila Singh   +4 more
openalex   +1 more source