Results 21 to 30 of about 97,240 (266)

Ecotropic murine leukemia virus-induced fusion of murine cells [PDF]

Journal of Virology, 1986
Extensive fusion occurs upon cocultivation of murine fibroblasts producing ecotropic murine leukemia viruses (MuLVs) with a large variety of murine cell lines in the presence of the polyene antibiotic amphotericin B, the active component of the antifungal agent Fungizone.
A, Pinter, T E, Chen, A, Lowy, N G, Cortez, S, Silagi   +4 more
openaire   +2 more sources

Tumorigenesis related to retroviral infections

Journal of Infection in Developing Countries, 2011
Retroviral infections are considered important risk factors for cancer development in humans since approximately 15-20% of cancer worldwide is caused by an infectious agent.
Maria Braoudaki, Fotini Tzortzatou-Stathopoulou   +1 more
doaj   +1 more source

Xenotropic murine leukemia virus-related virus is not associated with chronic fatigue syndrome in patients from different areas of the us in the 1990s

Virology Journal, 2011
Background In 2009, xenotropic murine leukemia virus-related virus (XMRV) was reported in 67% of patients with chronic fatigue syndrome (CFS) compared to 4% of controls.
Miller Frederick W, Goldbach-Mansky Raphaela, Kozak Christine A, Dale Janet K, Ali Mir A, Straus Stephen E, Cohen Jeffrey I   +6 more
doaj   +1 more source

Antibody responses against xenotropic murine leukemia virus-related virus envelope in a murine model. [PDF]

PLoS ONE, 2011
Xenotropic murine leukemia virus-related virus (XMRV) was recently discovered to be the first human gammaretrovirus that is associated with chronic fatigue syndrome and prostate cancer (PC).
Natalia Makarova, Chunxia Zhao, Yuanyuan Zhang, Sushma Bhosle, Suganthi Suppiah, Jeanne M Rhea, Natalia Kozyr, Rebecca S Arnold, Hinh Ly, Ross J Molinaro, Tristram G Parslow, Eric Hunter, Dennis Liotta, John Petros, Jerry L Blackwell   +14 more
doaj   +1 more source

Lack of infection with XMRV or other MLV-related viruses in blood, post-mortem brains and paternal gametes of autistic individuals. [PDF]

PLoS ONE, 2011
BackgroundAutistic spectrum disorder (ASD) is characterized by impaired language, communication and social skills, as well as by repetitive and stereotypic patterns of behavior. Many autistic subjects display a dysregulation of the immune system which is
Carla Lintas, Francesco Guidi, Barbara Manzi, Antonio Mancini, Paolo Curatolo, Antonio M Persico   +5 more
doaj   +1 more source

Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus

Retrovirology, 2007
Background Mutations of an alternative splice donor site located within the gag region has previously been shown to broaden the pathogenic potential of the T-lymphomagenic gammaretrovirus Moloney murine leukemia virus, while the equivalent mutations in ...
Quintanilla-Martinez Leticia, Kunder Sandra, Lund Anders H, Sørensen Annette, Schmidt Jörg, Wang Bruce, Wabl Matthias, Pedersen Finn   +7 more
doaj   +1 more source

Co-infection with the friend retrovirus and mouse scrapie does not alter prion disease pathogenesis in susceptible mice. [PDF]

PLoS ONE, 2012
Prion diseases are fatal, transmissible neurodegenerative diseases of the central nervous system. An abnormally protease-resistant and insoluble form (PrP(Sc)) of the normally soluble protease-sensitive host prion protein (PrP(C)) is the major component ...
Pascal Leblanc, Kim Hasenkrug, Anne Ward, Lara Myers, Ronald J Messer, Sandrine Alais, Andrew Timmes, Suzette A Priola   +7 more
doaj   +1 more source

Characterization of recombinant murine leukemia virus integrase [PDF]

Journal of Virology, 1995
Retroviral integration involves two DNA substrates that play different roles. The viral DNA substrate is recognized by virtue of specific nucleotide sequences near the end of a double-stranded DNA molecule. The target DNA substrate is recognized at internal sites with little sequence preference; nucleosomal DNA appears to be preferred for this role ...
I, Dotan, B P, Scottoline, T S, Heuer, P O, Brown   +3 more
openaire   +2 more sources

A Multicenter Blinded Analysis Indicates No Association between Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus

mBio, 2012
The disabling disorder known as chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) has been linked in two independent studies to infection with xenotropic murine leukemia virus-related virus (XMRV) and polytropic murine leukemia virus (pMLV).
Harvey J. Alter, Judy A. Mikovits, William M. Switzer, Francis W. Ruscetti, Shyh-Ching Lo, Nancy Klimas, Anthony L. Komaroff, Jose G. Montoya, Lucinda Bateman, Susan Levine, Daniel Peterson, Bruce Levin, Maureen R. Hanson, Afia Genfi, Meera Bhat, HaoQiang Zheng, Richard Wang, Bingjie Li, Guo-Chiuan Hung, Li Ling Lee, Stephen Sameroff, Walid Heneine, John Coffin, Mady Hornig, W. Ian Lipkin   +24 more
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source