Results 21 to 30 of about 72,711 (261)

Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus

open access: yesRetrovirology, 2007
Background Mutations of an alternative splice donor site located within the gag region has previously been shown to broaden the pathogenic potential of the T-lymphomagenic gammaretrovirus Moloney murine leukemia virus, while the equivalent mutations in ...
Quintanilla-Martinez Leticia   +7 more
doaj   +1 more source

Lack of infection with XMRV or other MLV-related viruses in blood, post-mortem brains and paternal gametes of autistic individuals. [PDF]

open access: yesPLoS ONE, 2011
BackgroundAutistic spectrum disorder (ASD) is characterized by impaired language, communication and social skills, as well as by repetitive and stereotypic patterns of behavior. Many autistic subjects display a dysregulation of the immune system which is
Carla Lintas   +5 more
doaj   +1 more source

A Multicenter Blinded Analysis Indicates No Association between Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus

open access: yesmBio, 2012
The disabling disorder known as chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) has been linked in two independent studies to infection with xenotropic murine leukemia virus-related virus (XMRV) and polytropic murine leukemia virus (pMLV).
Harvey J. Alter   +24 more
doaj   +1 more source

Chronic fatigue syndrome: Xenotropic murine leukemia virus-related virus, murine leukemia virus, both, or neither? [PDF]

open access: yesProceedings of the National Academy of Sciences, 2010
Lo et al. (1) report murine leukemia virus (MLV)-related sequences in peripheral blood mononuclear cell DNA and plasma RNA derived from patients with chronic fatigue syndrome (CFS). This follows a series of articles (2–5) that failed to confirm the detection of xenotropic murine leukemia virus-related virus (XMRV) sequences in CFS, as reported by ...
Myra McClure   +3 more
openaire   +2 more sources

Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms

open access: yesRetrovirology, 2012
Background One of the unique features of gammaretroviruses is that they contain an additional extended form of Gag, glyco-gag, which initiates in the leader sequence.
Nitta Takayuki   +5 more
doaj   +1 more source

Characterization of recombinant murine leukemia virus integrase [PDF]

open access: yesJournal of Virology, 1995
Retroviral integration involves two DNA substrates that play different roles. The viral DNA substrate is recognized by virtue of specific nucleotide sequences near the end of a double-stranded DNA molecule. The target DNA substrate is recognized at internal sites with little sequence preference; nucleosomal DNA appears to be preferred for this role ...
Patrick O. Brown   +3 more
openaire   +3 more sources

Endogenous Murine Leukemia Viruses: Relationship to XMRV and Related Sequences Detected in Human DNA Samples

open access: yesAdvances in Virology, 2011
Xenotropic-murine-leukemia-virus-related virus (XMRV) was the first gammaretrovirus to be reported in humans. The sequence similarity between XMRV and murine leukemia viruses (MLVs) was consistent with an origin of XMRV from one or more MLVs present as ...
Oya Cingöz, John M. Coffin
doaj   +1 more source

Frequent Infection of Human Cancer Xenografts with Murine Endogenous Retroviruses in Vivo

open access: yesViruses, 2015
Infection of human cancer xenografts in mice with murine leukemia viruses (MLVs) is a long-standing observation, but the likelihood of infection in vivo and its biological consequences are poorly understood.
Asif Naseer   +10 more
doaj   +1 more source

The saga of XMRV: a virus that infects human cells but is not a human virus

open access: yesEmerging Microbes and Infections, 2014
Xenotropic murine leukemia virus-related virus (XMRV) was discovered in 2006 in a search for a viral etiology of human prostate cancer (PC). Substantial interest in XMRV as a potentially new pathogenic human retrovirus was driven by reports that XMRV ...
Maribel Arias, Hung Fan
doaj   +1 more source

Phylogenetic Relationship of the Complete Rauscher Murine Leukemia Virus Genome with Other Murine Leukemia Virus Genomes

open access: yesVirology, 1997
We report the complete nucleotide sequence of the genome of Rauscher murine leukemia virus (R-MuLV), the replication-competent helper virus present in the Rauscher virus complex, and its phylogenetic relationship with other murine leukemia virus genomes. An overall sequence identity of 97.6% was found between R-MuLV and the Friend helper virus (F-MuLV),
Temple F. Smith   +4 more
openaire   +3 more sources

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