Results 21 to 30 of about 72,711 (261)
Background Mutations of an alternative splice donor site located within the gag region has previously been shown to broaden the pathogenic potential of the T-lymphomagenic gammaretrovirus Moloney murine leukemia virus, while the equivalent mutations in ...
Quintanilla-Martinez Leticia+7 more
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Lack of infection with XMRV or other MLV-related viruses in blood, post-mortem brains and paternal gametes of autistic individuals. [PDF]
BackgroundAutistic spectrum disorder (ASD) is characterized by impaired language, communication and social skills, as well as by repetitive and stereotypic patterns of behavior. Many autistic subjects display a dysregulation of the immune system which is
Carla Lintas+5 more
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The disabling disorder known as chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) has been linked in two independent studies to infection with xenotropic murine leukemia virus-related virus (XMRV) and polytropic murine leukemia virus (pMLV).
Harvey J. Alter+24 more
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Chronic fatigue syndrome: Xenotropic murine leukemia virus-related virus, murine leukemia virus, both, or neither? [PDF]
Lo et al. (1) report murine leukemia virus (MLV)-related sequences in peripheral blood mononuclear cell DNA and plasma RNA derived from patients with chronic fatigue syndrome (CFS). This follows a series of articles (2–5) that failed to confirm the detection of xenotropic murine leukemia virus-related virus (XMRV) sequences in CFS, as reported by ...
Myra McClure+3 more
openaire +2 more sources
Background One of the unique features of gammaretroviruses is that they contain an additional extended form of Gag, glyco-gag, which initiates in the leader sequence.
Nitta Takayuki+5 more
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Characterization of recombinant murine leukemia virus integrase [PDF]
Retroviral integration involves two DNA substrates that play different roles. The viral DNA substrate is recognized by virtue of specific nucleotide sequences near the end of a double-stranded DNA molecule. The target DNA substrate is recognized at internal sites with little sequence preference; nucleosomal DNA appears to be preferred for this role ...
Patrick O. Brown+3 more
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Xenotropic-murine-leukemia-virus-related virus (XMRV) was the first gammaretrovirus to be reported in humans. The sequence similarity between XMRV and murine leukemia viruses (MLVs) was consistent with an origin of XMRV from one or more MLVs present as ...
Oya Cingöz, John M. Coffin
doaj +1 more source
Frequent Infection of Human Cancer Xenografts with Murine Endogenous Retroviruses in Vivo
Infection of human cancer xenografts in mice with murine leukemia viruses (MLVs) is a long-standing observation, but the likelihood of infection in vivo and its biological consequences are poorly understood.
Asif Naseer+10 more
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The saga of XMRV: a virus that infects human cells but is not a human virus
Xenotropic murine leukemia virus-related virus (XMRV) was discovered in 2006 in a search for a viral etiology of human prostate cancer (PC). Substantial interest in XMRV as a potentially new pathogenic human retrovirus was driven by reports that XMRV ...
Maribel Arias, Hung Fan
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We report the complete nucleotide sequence of the genome of Rauscher murine leukemia virus (R-MuLV), the replication-competent helper virus present in the Rauscher virus complex, and its phylogenetic relationship with other murine leukemia virus genomes. An overall sequence identity of 97.6% was found between R-MuLV and the Friend helper virus (F-MuLV),
Temple F. Smith+4 more
openaire +3 more sources