Absence of XMRV and closely related viruses in primary prostate cancer tissues used to derive the XMRV-infected cell line 22Rv1. [PDF]
PLoS ONE, 2012 The 22Rv1 cell line is widely used for prostate cancer research and other studies throughout the world. These cells were established from a human prostate tumor, CWR22, that was serially passaged in nude mice and selected for androgen independence.
Jaydip Das Gupta +7 more
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Transplacental transmission of a leukemogenic murine leukemia virus [PDF]
Journal of Virology, 1993 Recombinant inbred BXH-2 mice spontaneously produce a B-tropic murine leukemia virus (MuLV) beginning early in life and have a high incidence of spontaneous myeloid leukemia. These traits are not characteristic of the progenitor strains (C57BL/6J and C3H/HeJ) or of 11 other recombinant inbred BXH strains.
Bedigian, H G, Shepel, L A, Hoppe, P C
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No association between XMRV or related gammaretroviruses in Australian prostate cancer patients
Virology Journal, 2013 Background Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with prostate cancer (PC) and chronic fatigue syndrome (CFS).
Rezaei Simin D +4 more
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Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. [PDF]
PLoS Genetics, 2008 Intrinsic immunity relies on specific recognition of viral epitopes to mount a cell-autonomous defense against viral infections. Viral recognition determinants in intrinsic immunity genes are expected to evolve rapidly as host genes adapt to changing ...
Julie A Kerns +2 more
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Characterization of Leukemia-Inducing Genes Using a Proto-Oncogene/Homeobox Gene Retroviral Human cDNA Library in a Mouse In Vivo Model. [PDF]
PLoS ONE, 2015 The purpose of this research is to develop a method to screen a large number of potential driver mutations of acute myeloid leukemia (AML) using a retroviral cDNA library and murine bone marrow transduction-transplantation system.
Su Hwa Jang, Sohyun Lee, Hee Yong Chung
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The tale of xenotropic murine leukemia virus-related virus
Journal of General Virology, 2012 In 2006, a new retrovirus was isolated from prostate cancer patient tissue. Named xenotropic murine leukemia virus-related virus (XMRV), this was potentially the third class of retrovirus to be pathogenic in humans. XMRV made a more dramatic impact on the wider scientific community, and indeed the media, in 2009 when it was reported to be present in a ...
Kate N. Bishop, Harriet C. T. Groom
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Characterizationof Murine Leukemia Virus Restriction inMammals [PDF]
Journal of Virology, 2003 ABSTRACT Restriction of murine leukemia virus (MLV) was examined in cells from a range of mammals. All nonmurine restrictions were saturable blocks to N-tropic MLV infection, and several were prior to reverse transcription. We demonstrate restriction in cells from bat and show that if we express the murine restriction factor Fv1 in human ...
Benjamin Strange +7 more
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Testing Strategies for Detection of Xenotropic Murine Leukemia Virus-Related Virus Infection
Advances in Virology, 2011 Xenotropic murine leukemia virus-related virus (XMRV) is a newly identified gamma retrovirus and may be associated with prostate cancer- (PC) and chronic fatigue syndrome (CFS). Since its identification in 2006 and detection of polytropic murine lenkemia
Shixing Tang, Indira K. Hewlett
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Infection of XC cells by MLVs and Ebola virus is endosome-dependent but acidification-independent. [PDF]
PLoS ONE, 2011 Inhibitors of endosome acidification or cathepsin proteases attenuated infections mediated by envelope proteins of xenotropic murine leukemia virus-related virus (XMRV) and Ebola virus, as well as ecotropic, amphotropic, polytropic, and xenotropic murine
Haruka Kamiyama +9 more
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Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source