In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase [PDF]
, 2018 Human norovirus causes approximately 219,000 deaths annually, yet there are currently no antivirals available. A virtual screening of commercially available drug-like compounds (~300,000) was performed on the suramin and PPNDS binding-sites of the ...
Ferla, Salvatore +8 more
core +3 more sources
Transcriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytes [PDF]
, 2017 Zabeen Lateef +3 more
openalex +1 more source
Microbial risk assessment of drinking water based on hydrodynamic modelling of pathogen concentrations in source water [PDF]
, 2015 Norovirus contamination of drinking water sources is an important cause of waterborne disease outbreaks. Knowledge on pathogen concentrations in source water is needed to assess the ability of a drinking water treatment plant (DWTP) to provide safe ...
Dienus, O. +5 more
core +1 more source
In Vitro Replication of Human Norovirus
Viruses, 2019 Human norovirus (HuNoV) infection is a major cause of gastroenteritis all over the world. Despite this, these non-enveloped RNA viruses are poorly characterized due to the lack of robust and widely available HuNoV culture systems.
Sutonuka Bhar, Melissa K. Jones
doaj +1 more source
Analysis of RNA-Protein interactions involved in calicivirus translation and replication
, 2008 The interaction of host-cell nucleic acid-binding proteins with the genomes of positive-stranded RNA viruses is known to play a role in the translation and replication of many viruses.
Karakasiliotis, Ioannis +1 more
core +1 more source
cGAS-STING effectively restricts murine norovirus infection but antagonizes the antiviral action of N-terminus of RIG-I in mouse macrophages [PDF]
, 2021 Peifa Yu +5 more
openalex +1 more source
Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells [PDF]
, 2019 Harriet V Mears +5 more
openalex +1 more source
Recovery Optimization and Survival of the Human Norovirus Surrogates Feline Calicivirus and Murine Norovirus on Carpet [PDF]
, 2017 David Buckley +3 more
openalex +1 more source
Murine norovirus capsid plasticity – Glycochenodeoxycholic acid stabilizes P-domain dimers and triggers escape from antibody recognition [PDF]
, 2021 Robert Creutznacher +11 more
openalex +1 more source
MicroorganismsHuman norovirus (HuNoV) is a major causative agent of foodborne illness and causes acute viral gastroenteritis. This study aimed to compare the virucidal efficacies of alcohol-based disinfectants against HuNoV and its surrogates for murine norovirus and ...
Eri Hiraishi +4 more
doaj +1 more source