Results 111 to 120 of about 282,371 (382)

Hematology of Swiss mice (Mus musculus) of both genders and different ages.

open access: yesActa Cirurgica Brasileira, 2014
PURPOSE To describe the hematologic values of male and female, young and adult, Swiss mice (Mus musculus). METHODS Mus musculus (n=14) were randomly selected and separated by gender.
Tamy Ingrid Restell   +3 more
semanticscholar   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

Qualitative Assessment of Gene Expression in Affymetrix Genechip Arrays

open access: yes, 2006
Affymetrix Genechip microarrays are used widely to determine the simultaneous expression of genes in a given biological paradigm. Probes on the Genechip array are atomic entities which by definition are randomly distributed across the array and in turn ...
Ashkenazy   +26 more
core   +1 more source

Identification of transcription factor binding sites in promoter databases [PDF]

open access: yes, 2011
Transcription factors (TFs) are the proteins which regulates the expression of their target genes either in a positive or negative manner. TFs realize this task by binding to a specific DNA sequence contained in promoter regions, via their DNA binding ...
Dağ, Uğur   +5 more
core   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

open access: yesAdvanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu   +13 more
wiley   +1 more source

The impact of Kersen leaves (Muntingia calabura L.) extract on Mus musculus with hypercholesterolemia

open access: yesActa Biochimica Indonesiana
Background: Hyperlipidemia, a condition marked by elevated levels of total cholesterol and related lipids, poses significant health risks. The potential cholesterol-lowering effects of Kersen leaves (Muntingia calabura L.), which are rich in flavonoids,
Sion Benu   +3 more
doaj   +1 more source

Morfologia i formació del complexe sinaptinèmic a espermatòcits i oòcits de Mus musculus [PDF]

open access: yes, 1983
A method for the sequential study of synaptonemal complexes by light and electron microscopy has been used to characterize the synaptic process in mouse (Mus musculus) spermatocytes and oocytes.
Coll, Maria Dolors   +5 more
core  

Comparative chromosome painting discloses homologous Segments in distantly related mammals [PDF]

open access: yes, 1994
Comparative chromosome painting, termed ZOO-FISH, using DNA libraries from flow sorted human chromosomes 1,16,17 and X, and mouse chromosome 11 discloses the presence of syntenic groups in distantly related mammalian Orders ranging from primates (Homo
A Jauch   +56 more
core   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

open access: yesAdvanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang   +15 more
wiley   +1 more source

Identification of a novel betaherpesvirus in Mus musculus

open access: yesVirology Journal, 2009
Rodent betaherpesviruses vary considerably in genomic content, and these variations can result in a distinct pathogenicity. Therefore, the identification of unknown betaherpesviruses in house mice (Mus musculus), the most important rodent host species in
Ehlers Bernhard   +4 more
doaj   +1 more source

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