Results 111 to 120 of about 126,194 (261)
Journal of Applied Toxicology, EarlyView.ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac +2 more
wiley +1 more source
Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy +7 more
wiley +1 more source
FLEXED TAIL IN THE MOUSE, MUS MUSCULUS [PDF]
Genetics, 1933 H R, Hunt, R, Mixter, D, Permar
openaire +2 more sources
Familiarity and aggression shape long‐term associations and mortality risk in a solitary ungulate
Oikos, EarlyView.Periodic social interactions are important to animal fitness, even in solitary species. For solitary species, these interactions can be unexpected and shaped by previous encounters. Despite being aggressive and largely solitary, black rhinoceroses Diceros bicornis are commonly seen in groups, suggesting they may engage in more social behaviours than ...
Rachel M. Stein, Adrian M. Shrader
wiley +1 more source
Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development
PROTEOMICS, EarlyView.ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia +7 more
wiley +1 more source
Published as part of Denys, Christiane, Gabriel, Nadine W., Lalis, Aude & Jenkins, Paulina, 2024, Subfossil rodents and tenrecs of Children's Cave, Madagascar, pp. 796-839 in Journal of Natural History 58 (25 - 28) on pages 809-811, DOI: 10.1080/00222933.2024.2370663, http://zenodo.org/record ...
Denys, Christiane +3 more
openaire +1 more source
SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies
PROTEOMICS, EarlyView.ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà +10 more
wiley +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Pest Management Science, EarlyView.This study assesses the distribution and frequency of Vkorc1 polymorphisms in house mice and Norway rats in northeastern USA. House mice showed higher frequency of Vkorc1 mutations than Norway rats. The A32V and Y139F mutations are first reported in mice, and the L128V is newly reported in Norway rats.
Jin‐Jia Yu +6 more
wiley +1 more source