Results 141 to 150 of about 13,057 (254)

Pronounced Conformational Changes following Agonist Activation of the M3 Muscarinic Acetylcholine Receptor [PDF]

, 2005
Sung‐Jun Han, Fadi F. Hamdan, Soo‐Kyung Kim, Kenneth A. Jacobson, Lars Brichta, Lanh M. Bloodworth, Jian H. Li, Jürgen Wess   +7 more
openalex   +1 more source

Ischemia Impairs the Association Between Connexin 43 and M3 Subtype of Acetylcholine Muscarinic Receptor (M3-mAChR) in Ventricular Myocytes [PDF]

, 2006
Peng Yue, Yong Zhang, Zhimin Du, Jing Xiao, Zhenwei Pan, Ning Wang, Haiyan Yu, Wencai Ma, Hong Qin, Wenhui Wang, Dao‐Hong Lin, Baofeng Yang   +11 more
openalex   +1 more source

Regulation of Src family kinases by muscarinic acetylcholine receptors in heterologous cells and neurons

Frontiers in Molecular Neuroscience
Five muscarinic acetylcholine (mACh) receptor subtypes are divided into two classes: the M1 class (M1, M3, and M5) and the M2 class (M2 and M4). The former is coupled to Gq proteins, while the latter is coupled to Gi/o proteins.
Li-Min Mao, Lexi Young, Xiang-Ping Chu, John Q. Wang, John Q. Wang   +4 more
doaj   +1 more source

M3 Muscarinic Receptor Antagonists Inhibit Small Cell Lung Carcinoma Growth and Mitogen-Activated Protein Kinase Phosphorylation Induced by Acetylcholine Secretion [PDF]

, 2007
Pingfang Song, Harmanjatinder S. Sekhon, Allison Lu, Juan Arredondo, David Sauer, Courtney Gravett, Gregory P. Mark, Sergei A. Grando, Eliot R. Spindel   +8 more
openalex   +1 more source

M3 Muscarinic Acetylcholine Receptor Expression Confers Differential Cholinergic Modulation to Neurochemically Distinct Hippocampal Basket Cell Subtypes [PDF]

, 2010
Christian A. Cea-Del Rio, J. Josh Lawrence, Ludovic Tricoire, Ferenc Erdélyi, Gábor Szabó, Chris J. McBain   +5 more
openalex   +1 more source

Mogrol stimulates G-protein-coupled bile acid receptor 1 (GPBAR1/TGR5) and insulin secretion from pancreatic β-cells and alleviates hyperglycemia in mice

Scientific Reports
Target identification is a crucial step in elucidating the mechanisms by which functional food components exert their functions. Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the triterpenoid ...
Chisato Tanaka, Naoki Harada, Yoshiaki Teraoka, Hiroki Urushizaki, Yoh Shinmori, Teruaki Onishi, Yusuke Yotsumoto, Yuta Ito, Tomoya Kitakaze, Takashi Inui, Yuji Murata, Hiroshi Inui, Ryoichi Yamaji   +12 more
doaj   +1 more source

Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors [PDF]

, 2014
Pavel Michal, Esam E. El‐Fakahany, Vladimı́r Doležal   +2 more
openalex   +1 more source

Rooibos (Aspalathus linearis) extract, containing eriodictyol-6-C-β-d-glucoside as the active component, stimulates exocrine glands via the M3 muscarinic acetylcholine receptor

Journal of Functional Foods, 2019
We previously discovered that rooibos extract activates the M3 muscarinic acetylcholine receptor (M3R), a key component of exocrine secretion. In this study, we examined the rooibos extract for active components in vitro and monitored its fast-acting ...
Saori Nishimachi, Takao Iwai, Yoshitaka Nakamura, Kanako Yuyama-Masuda, Takuya Tsutsui, Noriyuki Monoi, Akira Uchiyama, Seiji Nakamura   +7 more
doaj  

Interaction of lithocholylcholine, a newly-synthesized chimera of acetylcholine and conjugated lithocholic acid, with M3 muscarinic receptors on cho cells

, 2000
Kunrong Cheng, Piotr Zimniak, Jean‐Pierre Raufman   +2 more
openalex   +1 more source

G fehérjék szerepe a húgyhólyag simaizom-működésének szabályozásában. = G protein-mediated regulation of urinary smooth muscle contractility. [PDF]

, 2009
Eredményeink szerint élettani körülmények között a Gq/11 jelátviteli út (vélhetőleg az M3-receptorok által aktiválva) döntő szerepet játszik az acetilkolin simaizom-kontrakciót okozó hatásának közvetítésében és ezáltal a húgyhólyag működésének ...
Benyó, Zoltán
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