Muscarinic cannabinoid suppression of excitation, a novel form of coincidence detection
Pharmacological ResearchΔ9-tetrahydrocannabinol (THC), the chief psychoactive ingredient of cannabis, acts in the brain primarily via cannabinoid CB1 receptors. These receptors are implicated in several forms of synaptic plasticity – depolarization-induced suppression of ...
Michaela Dvorakova +2 more
doaj
Regulation of acetylcholine release from guinea-pig bladder urothelial cells - potential role in bladder filling sensations [PDF]
, 2014 Fry, C. H. +2 more
core +1 more source
Human HT-29 colon carcinoma cells contain mucarinic M\(_3\) receptors coupled to phosphoinositide metabolism [PDF]
, 1989 Five different musearlnie receptor subtypes ean be distinguished by the differenees in their amino aeid sequence, the eoupled signal transduetion system, pharmaeologieal binding properties and aetivation of ionie fluxes.
Kopp, R. +5 more
core
Modulation of lower urinary tract smooth muscle contraction and relaxation by the urothelium [PDF]
, 2018 Chess-Williams, Russ +2 more
core +1 more source
Ligand-Induced Activation of the M3-Muscarinic Acetylcholine Receptor
This thesis explores the computer-aided drug design of the M3-muscarinic acetylcholine receptor in three chapters. The first chapter focuses on molecular docking to identify novel agonists using the ZINC12 library. A model of the M3 receptor was built based on the M2 receptor.
openaire +1 more source
Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease
International Journal of COPD, 2018 Donald P Tashkin,1 Nicholas J Gross2 1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Department of Medicine, University Medical Research LLC, Saint Francis Hospital and Medical Center, Hartford, CT, USA Abstract:
Tashkin DP, Gross NJ
doaj
Rapid and Persistent Desensitization of m3 Muscarinic Acetylcholine Receptor-stimulated Phospholipase D [PDF]
, 1995 Martina Schmidt +6 more
openalex +1 more source
Muscarinic acetylcholine receptor M3 modulates odorant receptor activity via inhibition of β-arrestin-2 recruitment. [PDF]
Nat Commun, 2015 Jiang Y +4 more
europepmc +1 more source