Results 151 to 160 of about 27,064 (276)

Exploring the Antidiarrheal Properties of Papaya Leaf: Insights In Vivo Study in Mice-Model and In Silico Analysis at M3 Muscarinic Acetylcholine Receptor Interaction

open access: yesScientifica
Diarrhea caused by gut motility involves 5-HT3 serotonin receptor (5-HT3R) antagonist, M3 muscarinic acetylcholine receptor (M3-AchR), and H1 histamine receptor (H1R) via their respective agonist.
Nyi Mekar Saptarini   +2 more
doaj   +1 more source

Regulation of Src family kinases by muscarinic acetylcholine receptors in heterologous cells and neurons

open access: yesFrontiers in Molecular Neuroscience
Five muscarinic acetylcholine (mACh) receptor subtypes are divided into two classes: the M1 class (M1, M3, and M5) and the M2 class (M2 and M4). The former is coupled to Gq proteins, while the latter is coupled to Gi/o proteins.
Li-Min Mao   +4 more
doaj   +1 more source

Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors. [PDF]

open access: yes, 2011
BACKGROUND: Enteric neurotransmitters that act at G protein-coupled receptors (GPCRs) are well known to acutely promote epithelial Cl(-) and fluid secretion.
Bertelsen, Lone S   +6 more
core   +1 more source

Determination of Region-Specific Roles of the M3 Muscarinic Acetylcholine Receptor in Gastrointestinal Motility [PDF]

open access: green, 2022
Yoko Igarashi-Hisayoshi   +10 more
openalex   +1 more source

Mogrol stimulates G-protein-coupled bile acid receptor 1 (GPBAR1/TGR5) and insulin secretion from pancreatic β-cells and alleviates hyperglycemia in mice

open access: yesScientific Reports
Target identification is a crucial step in elucidating the mechanisms by which functional food components exert their functions. Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the triterpenoid ...
Chisato Tanaka   +12 more
doaj   +1 more source

Author response: Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor

open access: gold, 2021
Anja Flöser   +6 more
openalex   +1 more source

Protective role of M3 muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury [PDF]

open access: gold, 2023
Yoko Igarashi-Hisayoshi   +7 more
openalex   +1 more source

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