Results 141 to 150 of about 13,541 (253)

Mice Lacking M1 and M3 Muscarinic Acetylcholine Receptors Have Impaired Odor Discrimination and Learning [PDF]

, 2017
Wilson Chan, Sanmeet Singh, Taj Keshav, Ramita Dewan, Christian Eberly, Robert K. Maurer, Alexia Nunez-Parra, Ricardo C. Araneda   +7 more
openalex   +1 more source

The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families

Molecular Pharmacology
The M3 muscarinic acetylcholine receptor (M3R) is a G protein-coupled receptor (GPCR) that regulates important physiologic processes, including vascular tone, bronchoconstriction, and insulin secretion. It is expressed on a wide variety of cell types, including pancreatic beta, smooth muscle, neuronal, and immune cells.
Jeffrey S. Smith, Ari S. Hilibrand, Meredith A. Skiba, Andrew N. Dates, Victor G. Calvillo-Miranda, Andrew C. Kruse   +5 more
openaire   +2 more sources

Exploring the Antidiarrheal Properties of Papaya Leaf: Insights In Vivo Study in Mice-Model and In Silico Analysis at M3 Muscarinic Acetylcholine Receptor Interaction

Scientifica
Diarrhea caused by gut motility involves 5-HT3 serotonin receptor (5-HT3R) antagonist, M3 muscarinic acetylcholine receptor (M3-AchR), and H1 histamine receptor (H1R) via their respective agonist.
Nyi Mekar Saptarini, Faruk Jayanto Kelutur, Mary Jho-Anne Tolentino Corpuz   +2 more
doaj   +1 more source

Investigation of M3 muscarinic acetylcholine receptor expression in placentas of smoking women

Perinatal Journal
Objective: This study examined M3 muscarinic acetylcholine receptor expression in placentas of women who smoked during pregnancy and explored the affected signaling pathways via network and functional annotation analyses. Methods: Placenta samples from 45 control subjects and 45 individuals who smoked during pregnancy were fixed in zinc-formalin and em-
Esma Yıldırım, Gül Ebru Aydeniz Acar, Zeynep Türe, Ayşegül Aşır, Fırat Aşır, Tuğcan Korak, Serhat Ege   +6 more
openaire   +1 more source

Chronic exposure to the anti-M3 muscarinic acetylcholine receptor autoantibody in pemphigus vulgaris contributes to disease pathophysiology [PDF]

, 2022
Alex I. Chernyavsky, Mykhailo M. Khylynskyi, Krupa G. Patel, Sergei A. Grando   +3 more
openalex   +1 more source

Regulation of Src family kinases by muscarinic acetylcholine receptors in heterologous cells and neurons

Frontiers in Molecular Neuroscience
Five muscarinic acetylcholine (mACh) receptor subtypes are divided into two classes: the M1 class (M1, M3, and M5) and the M2 class (M2 and M4). The former is coupled to Gq proteins, while the latter is coupled to Gi/o proteins.
Li-Min Mao, Lexi Young, Xiang-Ping Chu, John Q. Wang, John Q. Wang   +4 more
doaj   +1 more source

Distinct signal transduction and cellular responses following activation of m1 and m3 muscarinic acetylcholine receptors

, 1995
Michihisa Tohda, Haruhiro Higashida, Yasuyuki Nomura   +2 more
openalex   +1 more source

Mogrol stimulates G-protein-coupled bile acid receptor 1 (GPBAR1/TGR5) and insulin secretion from pancreatic β-cells and alleviates hyperglycemia in mice

Scientific Reports
Target identification is a crucial step in elucidating the mechanisms by which functional food components exert their functions. Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the triterpenoid ...
Chisato Tanaka, Naoki Harada, Yoshiaki Teraoka, Hiroki Urushizaki, Yoh Shinmori, Teruaki Onishi, Yusuke Yotsumoto, Yuta Ito, Tomoya Kitakaze, Takashi Inui, Yuji Murata, Hiroshi Inui, Ryoichi Yamaji   +12 more
doaj   +1 more source

Autoimmune response to M3 muscarinic acetylcholine receptor in Sjögren’s syndrome [PDF]

, 2013
科学研究費助成事業(学術研究助成基金助成金)研究成果報告書：若手研究(B)2011-2012課題番号 ...
Tsuboi Hiroto, 坪井 洋人
core  

Functional Expression of M3, a Muscarinic Acetylcholine Receptor Subtype, in Taste Bud Cells of Mouse Fungiform Papillae [PDF]

, 2007
Kohgaku Eguchi, Yoshitaka Ohtubo, Kiyonori Yoshii   +2 more
openalex   +1 more source