Results 11 to 20 of about 26,727 (247)
Isosterism and Bioisosterism Case Studies with Muscarinic Agonists
CHIMIA, 1992 The synthesis and activity of enantiomerically pure analogues of pilocarpine and muscarinic agonists with the azabicyclo[2.2.1]heptane skeleton is described.
Philipp Floersheim +2 more
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Is muscarinic receptor agonist effective and tolerant for schizophrenia?
BMC PsychiatryBackground Several randomized clinical trials (RCTs) have recently examined the efficacy and tolerability of muscarinic receptor agonists in schizophrenia. However, whether therapeutics targeting muscarinic receptors improve symptom management and reduce
Xiaonan Guo +3 more
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Xanomeline-Trospium and Muscarinic Involvement in Schizophrenia
Neuropsychiatric Disease and Treatment, 2023 Neil Kidambi,* Omar H Elsayed,* Rif S El-Mallakh* Mood Disorders Research Program, Depression Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY, 40202, USA*These authors ...
Kidambi N, Elsayed OH, El-Mallakh RS
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Distribution of dissociation constant values of muscarinic agonists
Journal of Pharmacy and Pharmacology, 1989 AbstractThe frequency distributions of dissociation constant values of some muscarinic agonists (carbachol, muscarone and cis-2-methyl-5-trimethylammoniummethyl-1,3-oxathiolane) obtained on guinea-pig ileum and atria and rat urinary bladder have been examined to see if the means of the dissociation constant values and the statistical tests for their ...
A, Lucchelli, C, Boselli, E, Grana
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The interaction of tiotropium with long lasting β2-agonists on lung cell function [PDF]
, 2013 The major question addressed in this thesis was to find the mechanism(s) by which muscarinic receptors interact with β2-adrenergic receptors in human airway fibroblasts.
Costa, Luigi
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Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells [PDF]
, 1992 We investigated whether the stimulation of human granulosa-lutein cells with muscarinic and nicotinic receptor agonists can cause increases in intracellular free calcium (Ca2+), using Fura-2 microfluorimetry.
Föhr, K. J. +3 more
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Cell Reports, 2019 Summary: Lymphatic vessels (LVs) are important in the regulation of tissue fluid homeostasis and the pathogenesis of tumor progression. We investigated the innervation of LVs and the response to agonists and antagonists of the autonomic nervous system in
Samia B. Bachmann +8 more
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Markers of muscarinic deficit for individualized treatment in schizophrenia
Frontiers in Psychiatry, 2023 Recent clinical studies have shown that agonists at muscarinic acetylcholine receptors effectively reduce schizophrenia symptoms. It is thus conceivable that, for the first time, a second substance class of procholinergic antipsychotics could become ...
Heiner Stuke, Heiner Stuke
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Eosinophil-mediated cholinergic nerve remodeling [PDF]
, 2006 Eosinophils are observed to localize to cholinergic nerves in a variety of inflammatory conditions such as asthma, rhinitis, eosinophilic gastroenteritis, and inflammatory bowel disease, where they are also responsible for the induction of cell ...
McLean, W.G. +28 more
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Radioprotective effect of lidocaine on neurotransmitter agonist-induced secretion in irradiated salivary glands. [PDF]
, 2013 Previously we verified the radioprotective effect of lidocaine on the function and ultrastructure of salivary glands in rabbits. However, the underlying mechanism of lidocaine's radioprotective effect is unknown.
Klinger, Matthias +22 more
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