Results 51 to 60 of about 26,727 (247)

Review of nutrition management of pediatric intestinal pseudo‐obstruction

Nutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman, Raisa Rani James, Bushra El‐Amaireh, Andrea Adler, Kadakkal Radhakrishnan, Sujithra Velayuthan   +5 more
wiley   +1 more source

Pharmacological modulation of fish-induced depth selection in D. magna: the role of cholinergic and GABAergic signalling

Scientific Reports, 2021
Animal behaviour is closely related to individual fitness, which allows animals to choose suitable mates or avoid predation. The central nervous system regulates many aspects of animal behaviour responses.
Juliette Bedrossiantz, Inmaculada Fuertes, Demetrio Raldua, Carlos Barata   +3 more
doaj   +1 more source

Error Traps in Pediatric Neuromuscular Block

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa, Debra Faulk, Vinicius Caldeira Quintao, Niekoo Abbasian, Hans D. de Boer, Ricardo Vieira Carlos   +5 more
wiley   +1 more source

Activation mechanisms of muscarinic M1 receptor by atypical agonists [PDF]

, 2016
Atypical agonists of muscarinic receptors bind to individual receptor subtypes with comparable affinity but activate them selectively to a certain extent.
Randáková, Alena
core  

Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3β inhibition and in neurons

, 2000
Muscarinic agonists alter the metabolism of amyloid precursor protein, leading to an increase in α-secretase cleavage and a decreased production of amyloidogenic peptides; suggesting that these compounds might modify the Alzheimer's disease process.
Spink, J. M., Lovestone, S., Spink, J M, Olesen, O F, Forlenza, O V, Olesen, O. F., Dayanandan, R., Anderton, B H, Forlenza, O. V., Dayanandan, R, Lovestone, S, Anderton, B. H.   +11 more
core   +1 more source

Acetylcholine induces stem cell properties of gastric cancer cells of diffuse type

Tumor Biology, 2018
Gastric cancer is the third leading cause of cancer-related death worldwide, but the mechanisms of gastric carcinogenesis are not completely understood.
Phu Hung Nguyen, Yann Touchefeu, Tony Durand, Philippe Aubert, Emilie Duchalais, Stanislas Bruley des Varannes, Christine Varon, Michel Neunlist, Tamara Matysiak-Budnik   +8 more
doaj   +1 more source

An Age‐Friendly Approach to Caring for Chronic Lung Disease in the Ambulatory Setting

Respirology, EarlyView.
ABSTRACT Many common chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD), have much greater prevalence among older adults and as a result, pose a substantial burden of morbidity, disability, and mortality. The care of older adults with chronic lung disease necessitates an age‐friendly approach
Angela O. Suen, Lauren R. Pollack, C. Adrian Austin, Leah J. Witt   +3 more
wiley   +1 more source

Synthesis and pharmacological characterization of enantiomerically pure muscarinic agonists: difluoromuscarines

, 1997
The four homochiral 4-deoxy-4,4-difluoromuscarine stereoisomers (difluoromuscarines) were prepared in very high enantiomeric excess. A convenient sequence based on the use of natural as well as “unnatural” ethyl lactate allowed the synthesis of target ...
Cavagna, Roberto, MARUCCI, Gabriella, De Micheli, Marco, Angeli, Piero, De Amici, Marco, Gamba, Anna, CANTALAMESSA, Franco, Conti, Paola   +7 more
core   +2 more sources

In vitro Comparison of the Intrinsic Activity of Functional Antagonism between β-agonists and Spasmogens in the Guinea-pig Tracheal Muscle

Allergology International, 2005
Background: The bronchodilating action of β-agonists depends on the tone of airway smooth muscle or on spasmogen. To estimate the precise intrinsic activity of β-agonists, relaxation responses should be examined on maximally contracted airway smooth ...
Yuichiro Kamikawa, Naomi Takayama
doaj   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source