Results 151 to 160 of about 362,047 (272)

Bioinspired Mechanisms and Actuation of Soft Robotic Crawlers

open access: yesAdvanced Science, EarlyView.
Researchers have been developing soft materials and robotic crawlers inspired by soft‐bodied animals to mimic effective crawling in complex environments. This review explores the state‐of‐the‐art in soft crawlers, highlighting the interaction between materials, crawling mechanisms, actuation, and applications. The review concludes by providing insights
Min Pan   +6 more
wiley   +1 more source

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

open access: yesAdvanced Science, EarlyView.
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing   +4 more
wiley   +1 more source

Improved Orthogonality in Naphthalimide/Cyanine Dyad Boosts Superoxide Generation: a Tumor‐Targeted Type‐I Photosensitizer for Photodynamic Therapy of Tumor by Inducing Ferroptosis

open access: yesAdvanced Science, EarlyView.
A tumor‐targeted, renal‐metabolized, and less O2‐dependent Type‐I photosensitizer is presented for photodynamic therapy of tumors. The formation of an intramolecular sandwich‐like π–π assembly ensures its rigid orthogonal geometry, thereby improving the superoxide (O2•−)‐generating ability, promoting the intracellular formation of hydroxy radical (HO•),
Guangxiao Yao   +3 more
wiley   +1 more source

Comprehensive genetic screening for vascular Ehlers–Danlos syndrome through an amplification‐based next‐generation sequencing system

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 37-51, January 2023., 2023
Abstract Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder (HCTD) characterized by arterial dissection/aneurysm/rupture, sigmoid colon rupture, or uterine rupture. Diagnosis is confirmed by detecting heterozygous variants in COL3A1.
Tomomi Yamaguchi   +25 more
wiley   +1 more source

In memoriam: Susan Abmayr (1956–2019) – “What do we do? Whatever it takes!”

open access: yesSkeletal Muscle, 2019
Erika R. Geisbrecht, Mary K. Baylies
doaj   +1 more source

Hyperpolarized <sup>13</sup>C-MRS can Quantify Lactate Production and Oxidative PDH Flux in Murine Skeletal Muscle During Exercise. [PDF]

open access: yesNMR Biomed
Curtis MK   +10 more
europepmc   +1 more source

Biomimetic Microstructured Scaffold with Release of Re‐Modified Teriparatide for Osteoporotic Tendon‐to‐Bone Regeneration via Balancing Bone Homeostasis

open access: yesAdvanced Science, EarlyView.
This study develops RPTH by re‐modifying teriparatide and designs a biomimetic microstructured scaffold (BMRP) loaded with RPTH to address osteoporotic tendon‐to‐bone interface repair. The BMRP restores tissue architecture by balancing bone homeostasis and remodeling the microstructure, achieving functional recovery in an osteoporotic rotator cuff tear
Chengzhong Xu   +11 more
wiley   +1 more source

Anticipatory banking of samples enables diagnosis of adenylosuccinase deficiency following molecular autopsy in an infant with vacuolating leukoencephalopathy

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 234-237, January 2023., 2023
Abstract Adenylosuccinase deficiency is a rare inborn error of metabolism. We present a newborn who died at 52 days of age with clinical features suggestive of severe epileptic encephalopathy and leukodystrophy of unknown cause. Post‐mortem examination showed an unusual vacuolar appearance of the brain.
Spatikha Sitaram   +11 more
wiley   +1 more source

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