Results 241 to 250 of about 2,572,202 (339)

Amino acid supplementation accelerates resolution of exercise-induced phagocyte infiltration in human skeletal muscle. [PDF]

J Int Soc Sports Nutr
Ye M, Condello G, Chao KC, Yang HT, Huang CY, Lai LF, Dewi L, Liao YC, Nicholls A, Ji F, Chi NF, Kuo CH.   +11 more
europepmc   +1 more source

Gut Microbiota Contribute to Age-Related Changes in Skeletal Muscle Size, Composition, and Function: Biological Basis for a Gut-Muscle Axis

Calcified Tissue International, 2018
Gregory J. Grosicki, R. Fielding, M. Lustgarten   +2 more
semanticscholar   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Inter-Organ Crosstalk and Regulatory Mechanisms of Skeletal Muscle-Derived Extracellular Vesicles in Systemic Metabolic Homeostasis. [PDF]

J Cell Mol Med
Wu Z, Gao Y, Chen Q, Yuan L.
europepmc   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Perturbation of multiprotein complexes in skeletal muscle induces protective proteases in the CNS that degrade pathogenic proteins. [PDF]

NPJ Aging
Rai M, Baddeley HJE, Chuang CL, Platt A, Curley M, Finkelstein D, Demontis F.   +6 more
europepmc   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

Advanced Science, EarlyView.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li, Jia Li, Anshu Tang, Cong Li, Chao Zhang, Congcong Zhang, Yun‐Cai Liu   +6 more
wiley   +1 more source

The impact of cellular senescence on aging skeletal muscle. [PDF]

Front Cell Dev Biol
Kamal M, Bevington R, Johnson A, Parise G.   +3 more
europepmc   +1 more source

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

Advanced Science, EarlyView.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan−Shan Wang, Bo O. Zhou   +4 more
wiley   +1 more source

Critical role of mitochondrial aconitase in skeletal muscle maturation. [PDF]

Sci Rep
Fukawa T, Takata M, Kishida K, Sugiura K, Suzuki M, Tsuda H, Sakakibara I, Uchida T, Rahman MM, Ulla A, Sairyo K, Sato T, Ikemoto-Uezumi M, Uezumi A, Nikawa T.   +14 more
europepmc   +1 more source