Background We previously reported that Wnt5a/CaMKIIδ (calcium/calmodulin-dependent protein kinase II delta) pathway was involved in the embryonic tongue deformity induced by excess retinoic acid (RA).
Bo Liu+9 more
doaj +1 more source
Metabolic reprogramming promotes myogenesis during aging [PDF]
Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a ...
Belli, R+11 more
core +3 more sources
THE TEMPERATURE OF SKELETAL MUSCLES [PDF]
n ...
openaire +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Muscle as a meta-material operating near a critical point [PDF]
Passive mechanical response of skeletal muscles at fast time scales is dominated by long range interactions inducing cooperative behavior without breaking the detailed balance. This leads to such unusual "material properties" as negative equilibrium stiffness and different behavior in force and displacement controlled loading conditions. Our fitting of
arxiv +1 more source
Human cachexia induces changes in mitochondria, autophagy and apoptosis in the skeletal muscle [PDF]
Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle mass due to imbalance between protein synthesis and degradation, which is related with poor prognosis and compromised quality of life.
Alcantara, P. S.+9 more
core +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
TNF-α- and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism
Background Muscle atrophy associated with various pathophysiological conditions represents a major health problem, because of its contribution to the deterioration of patient status and its effect on mortality.
De Larichaudy Joffrey+11 more
doaj +1 more source
In plane quantification of in vivo muscle elastic anisotropy factor by steered ultrasound pushing beams [PDF]
Skeletal muscles are organized into distinct layers and exhibit anisotropic characteristics across various scales. Assessing the arrangement of skeletal muscles may provide valuable biomarkers for diagnosing muscle related pathologies and evaluating the efficacy of clinical interventions.
arxiv
Vitamin D supplementation does not improve human skeletal muscle contractile properties in insufficient young males [PDF]
Vitamin D may be a regulator of skeletal muscle function, although human trials investigating this hypothesis are limited to predominantly elderly populations.
Close, Graeme L+7 more
core +1 more source