Results 111 to 120 of about 1,728,740 (303)

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo

Advanced Healthcare Materials, EarlyView.
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer, H. Mutlu, C. Charmette, E. Randrianaridera, Z. Adaidi, R. Hedna, L. Pieuchot, I. Pluvy, K. Anselme, N. Couturier, J. P. Mericq, A. Ponche, I. Brigaud   +12 more
wiley   +1 more source

Synthesis of extracellular matrix components by human ciliary muscle cells in culture [PDF]

, 1992
The production and spatial organization of connective tissue components in ciliary muscle cell cultures was studied with immunohistochemical and ultrastructural methods.
Baur, A., Tamm, Ernst R., Lütjen-Drecoll, E.   +2 more
core   +1 more source

Senescence as a Driver of Smooth Muscle Cell Plasticity and Atherosclerosis: Mechanisms and Therapeutic Opportunities

Cells
Cell senescence is increasingly recognized as a key driver of atherosclerosis progression. Senescent smooth muscle cells (SMCs) lose their proliferative capacity and adopt a pro-inflammatory profile, contributing to impaired vessel repair and weakening ...
Lisa Steegen, Mandy O. J. Grootaert
doaj   +1 more source

CNP-pGC-cGMP-PDE3-cAMP Signal Pathway Upregulated in Gastric Smooth Muscle of Diabetic Rats

Gastroenterology Research and Practice, 2015
Our previous studies have shown that CNP-NPR-B/pGC-cGMP is upregulated in the diabetic rats. The present study was designed to determine whether the upregulation of CNP-NPR-B/pGC-cGMP signal pathway affects cGMP-PDE3-cAMP signal pathway in diabetic ...
Ying-Lan Cai, Mo-Han Zhang, Xu Huang, Jing-Zhi Jiang, Li-Hua Piao, Zheng Jin, Wen-Xie Xu   +6 more
doaj   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Concerted upregulation of CLP36 and smooth muscle actin protein expression in human endometrium during decidualization [PDF]

, 2005
The human endometrium prepares for implantation of the blastocyst by reorganization of its whole cellular network. Endometrial stroma cells change their phenotype starting around the 23rd day of the menstrual cycle.
Neumaier-Wagner, Peruka, Huppertz, Berthold, Goyal, Pankaj, Rath, Werner, Miehe, Ulrich, Kadyrov, Mamed, Alfer, Joachim, Miehe, U;Neumaier-Wagner, P;Kadyrov, M;Goyal, P;Alfer, J;Rath, W;Huppertz, B   +7 more
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source

Three-dimensional-mapping of smooth muscle morphogenesis in the vertebrate gastrointestinal tract

Scientific Reports
Gastrointestinal (GI) motility depends on smooth muscle contractions to propel contents through the digestive tract. GI muscle is organized into two perpendicular layers: the inner circular smooth muscle (CSM) and the outer longitudinal smooth muscle ...
Salomé Ruiz Demoulin, Amandine Falco, Norbert Chauvet, Pascal de Santa Barbara, Sandrine Faure   +4 more
doaj   +1 more source

Regulation of PDGFRα+ cells and ICC in progesterone-mediated slow colon transit in pregnant mice

Heliyon
Background: Progesterone can inhibit intestinal smooth muscle contraction; however, the specific mechanism remains unclear. Besides smooth muscle cells, smooth muscle has two important mesenchymal cells, namely interstitial cells of Cajal (ICC) and ...
Chen Lu, Hui Luo, Ye Wang, Shuang Jing, Jun Zhao, Kexin Zou, Fan Wu, Hao Ying   +7 more
doaj   +1 more source