Results 171 to 180 of about 788,671 (263)

Fibromyalgia: Chronic Pain Due to a Blood Dysfunction? [PDF]

Int J Mol Sci
Aloisi AM, Casini I.
europepmc   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui, Meng Yang, Chengli Yu, Haidong Zhang, Yuan Gong, Yang Hu, Yue Wang, Qingxin Yuan, An Pan, Jiepin Li, Yaowen Hu, Zecheng Jin, Xuemei Peng, Anyuan Wu, Junwei Wang, Qian Wang, Yinan Zhang, Lihong Hu   +17 more
wiley   +1 more source

Efficient wet-spinning of pre-aligned microtissues for 3D bioprinting complex tissue alignment. [PDF]

Biofabrication
Vogt CD, Broomhead JR, Kunisaki KY, Teegarden JM, Frett KL, Pacello KQ, Vitale AH, Panoskaltsis-Mortari A.   +7 more
europepmc   +1 more source

Progress and Perspectives in 2D Piezoelectric Materials for Piezotronics and Piezo‐Phototronics

Advanced Science, EarlyView.
This review examines advancements in 2D materials, focusing on their applications in piezotronics and piezo‐phototronics. It discusses key materials like TMDs, h‐BN, and phosphorene, highlighting their unique mechanical, electronic, and optical properties.
Fengyi Pang, Pin Zhao, Hyeon Yeong Lee, Dae‐Jin Kim, Xiangchun Meng, Yong Soo Cho, Sang‐Woo Kim   +6 more
wiley   +1 more source

Trehalose induces bladder smooth muscle hypercontractility in mice: involvement of oxidative stress and cellular senescence. [PDF]

Front Physiol
Lemos G, Fernandes CMAS, Watanabe IKM, Delbin MA, Silva FH, Calmasini FB.   +5 more
europepmc   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

Advanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation

Advanced Science, EarlyView.
This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren, Yangnan Hu, Xiaoqiong Ding, Menghui Liao, Tian Shen, Sixing Cao, Hui Zhang, Hong Cheng, Yanru Qi, Pan Feng, Xinyi Pang, Ling Lu, Huan Wang, Wenwen Liu, Renjie Chai, Lin Cheng   +15 more
wiley   +1 more source

A Method for Precisely Designing the Form of Double Eyelid in Double Eyelid Plasty. [PDF]

Plast Reconstr Surg Glob Open
Yin H, Yang H.
europepmc   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source