Results 241 to 250 of about 2,710,339 (310)
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Smooth-muscle contraction without smooth-muscle myosin
Nature Cell Biology, 2000Here we have used gene-targeting to eliminate expression of smooth-muscle myosin heavy chain. Elimination of this gene does not affect expression of non-muscle myosin heavy chain, and knockout individuals typically survive for three days. Prolonged activation, by KCl depolarisation, of intact bladder preparations from wild-type neonatal mice produces ...
Monika Kott +7 more
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Cytokeratins in smooth muscle cells and smooth muscle tumours
Histopathology, 1988A keratin positive metastatic leiomyosarcoma in the lung, which resulted in diagnostic error, is reported. The results of additional studies of 17 benign and malignant leiomyogenic tumours with various keratin antibodies are presented and discussed in the light of recent bibliographical data.
F. C. S. Ramaekers +2 more
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Canadian Journal of Physiology and Pharmacology, 1994
We have demonstrated that in dogs antigen sensitization results in alterations of contractile properties. These changes could account for the hyperresponsiveness reported in asthma. The failure of the muscle to relax could be another important factor responsible for maintaining high airway resistance.
Newman L. Stephens, H. Jiang
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We have demonstrated that in dogs antigen sensitization results in alterations of contractile properties. These changes could account for the hyperresponsiveness reported in asthma. The failure of the muscle to relax could be another important factor responsible for maintaining high airway resistance.
Newman L. Stephens, H. Jiang
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Urologic Clinics of North America, 2001
This article addresses smooth muscle physiology, electromechanical and pharmacomechanical coupling, computed-based interpretations, and the role of electromyography in the diagnosis of erectile dysfunction.
Bernd Kellner +3 more
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This article addresses smooth muscle physiology, electromechanical and pharmacomechanical coupling, computed-based interpretations, and the role of electromyography in the diagnosis of erectile dysfunction.
Bernd Kellner +3 more
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Physiological Reviews, 2003
Ca2+ sensitivity of smooth muscle and nonmuscle myosin II reflects the ratio of activities of myosin light-chain kinase (MLCK) to myosin light-chain phosphatase (MLCP) and is a major, regulated determinant of numerous cellular processes. We conclude that
A. Somlyo, A. Somlyo
semanticscholar +1 more source
Ca2+ sensitivity of smooth muscle and nonmuscle myosin II reflects the ratio of activities of myosin light-chain kinase (MLCK) to myosin light-chain phosphatase (MLCP) and is a major, regulated determinant of numerous cellular processes. We conclude that
A. Somlyo, A. Somlyo
semanticscholar +1 more source
Physiological roles and properties of potassium channels in arterial smooth muscle.
American Journal of Physiology, 1995This review examines the properties and roles of the four types of K+ channels that have been identified in the cell membrane of arterial smooth muscle cells.
Mark Nelson, J. Quayle
semanticscholar +1 more source
Acta Physiologica Scandinavica, 1997
In this paper, the control of vascular smooth muscle intracellular pH (pHi) and the mechanisms of importance for the vasodilation to acidosis are reviewed. The three transport pathways of importance for the control of pHi are a sodium‐coupled bicarbonate transport, a Na,H‐exchanger and a Cl,HCO3−exchange.
Hongli Peng, Christian Aalkjaer
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In this paper, the control of vascular smooth muscle intracellular pH (pHi) and the mechanisms of importance for the vasodilation to acidosis are reviewed. The three transport pathways of importance for the control of pHi are a sodium‐coupled bicarbonate transport, a Na,H‐exchanger and a Cl,HCO3−exchange.
Hongli Peng, Christian Aalkjaer
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Annual Review of Physiology, 1989
Muscle energetics now emcompasses several related areas. Historically, the approach of energetics was largely phenomenological and primarily involved quantitation of muscle heat production and mechanical output in order to define performance characteristics.
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Muscle energetics now emcompasses several related areas. Historically, the approach of energetics was largely phenomenological and primarily involved quantitation of muscle heat production and mechanical output in order to define performance characteristics.
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Vascular smooth muscle cell calcification is mediated by regulated exosome secretion.
Circulation Research, 2015RATIONALE Matrix vesicles (MVs), secreted by vascular smooth muscle cells (VSMCs), form the first nidus for mineralization and fetuin-A, a potent circulating inhibitor of calcification, is specifically loaded into MVs.
A. Kapustin +19 more
semanticscholar +1 more source
Urologic Clinics of North America, 1996
In the last several years, significant advances have been made in the understanding of bladder smooth muscle physiology. This article provides a summary for the clinician of current knowledge about the detrusor smooth muscle cell structure, function, and the relationship of structure to function in terms of bladder storage and physical properties such ...
Philippe E. Zimmern +2 more
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In the last several years, significant advances have been made in the understanding of bladder smooth muscle physiology. This article provides a summary for the clinician of current knowledge about the detrusor smooth muscle cell structure, function, and the relationship of structure to function in terms of bladder storage and physical properties such ...
Philippe E. Zimmern +2 more
openaire +3 more sources