Results 91 to 100 of about 1,263,304 (239)

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

Upscaling the Fabrication of Rod‐Shaped Microgels: A Microfluidic Method Combining Step‐Emulsification With Consecutive Droplet Confinement in Parallelized Microchannels

open access: yesAdvanced Materials, EarlyView.
A microfluidic method is presented which enables parallelized fabrication of rod‐shaped microgels, based on step‐emulsification (SE) droplet generation and subsequent droplet distribution and confinement, combined in a single device. Microgel rods are fabricated in parallel at different flow rates based on two light‐mediated crosslinking chemistries ...
Matthias Mork   +5 more
wiley   +1 more source

The role of muscle biopsy in investigating isolated muscle pain

open access: yes, 2007
Objective: To evaluate the muscle biopsy findings from 240 patients who had isolated muscle pain. Methods: Histopathology, immunohistochemistry for dystrophin, dystrophin-related proteins, major histocompatibility complex type I, and biochemical ...
BERTOLASI, LAURA   +6 more
core   +2 more sources

Transjugular liver biopsy: how good is it for accurate histological interpretation? [PDF]

open access: yes, 2006
Background: A transjugular liver biopsy (TJLB) specimen is often smaller or more fragmented than a percutaneous liver biopsy (PLB) specimen. Recently, for PLB, the minimum requirements to evaluate chronic hepatitis have been set at 20–25 mm length and 11
Leandro, G.   +8 more
core  

Diagnostic Value of Finger-Guided Prostate Nodule Biopsy Combined with Systemic Random Biopsy

open access: yes, 2011
Background/Pur-pose: The purpose of this study was to compare prostate cancer detection rates and pathology results, using the Gleason grading system, of 12-core systemic random transrectal ultrasound-guided prostate biopsy (SB) and 3-core finger-guided ...
CHIANG, I-NI;CHANG, SHANG-JEN;PU, YEONG-SHIAU;HUANG, KUO-HOW;YU, HONG-JENG;HUANG, CHAO-YUAN   +1 more
core   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

open access: yesAdvanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn   +17 more
wiley   +1 more source

Myotonia congenita and myoadenylate deaminase deficiency: case report

open access: yesArquivos de Neuro-Psiquiatria, 2003
Approximately 1-2% of the population has a deficiency of the enzyme myoadenylate deaminase. Early reports suggested that patients with myoadenylate deaminase deficiency had various forms of myalgia, and exercise intolerance.
Scola Rosana Herminia   +4 more
doaj  

Impaired muscle glycogen storage after muscle biopsy

open access: yes, 1988
To assess the effects of repeated needle biopsies on the rate of muscle glycogen repletion, eight male subjects were studied immediately after and 2 days after an exhaustive cycling bout.
D. L. Costill, W. J. Fink, D. R. Pearson
core   +1 more source

Collagen‐Based Gut‐on‐Chip for In Vitro Modeling of Intestinal Barrier Function and Host‐Pathogen Interactions

open access: yesAdvanced Materials Technologies, EarlyView.
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García   +4 more
wiley   +1 more source

Revertant fibres and dystrophin traces in Duchenne muscular dystrophy: Implication for clinical trials [PDF]

open access: yes, 2010
Duchenne muscular dystrophy (DMD) is characterised by the absence of dystrophin in muscle biopsies, although residual dystrophin can be present, either as dystrophin-positive (revertant) fibres or traces.
Main, M   +12 more
core  

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