Results 101 to 110 of about 159,171 (308)

Inhibition of FOXM1 Synergizes with BH3 Mimetics Venetoclax and Sonrotoclax in Killing Multiple Myeloma Cells through Repressing MYC Pathway

Advanced Science, EarlyView.
Relapsed and refractory multiple myeloma remains a major clinical challenge. This study shows that FOXM1 contributes to resistance against BH3 mimetics in multiple myeloma cells. The FOXM1 inhibitor NB73 enhances the effectiveness of BH3 mimetics by reducing FOXM1 expression and suppressing the MYC pathway.
Zhi Wen, Yidan Wang, Kathryn C. Fox, Adam M. Bissonnette, Luke F. Moat, Terrie E. Kitchner, Kelsey Springstroh, Sung Hoon Kim, Dagna S. Sheerar, Patcharon Tanawattanacharoen, Chady A. Leon, Seth O. Fagbemi, John A. Katzenellenbogen, Scott J. Hebbring, Benita S. Katzenellenbogen, Siegfried Janz, Adedayo A. Onitilo   +16 more
wiley   +1 more source

Estimating the time of human decomposition based on skeletal muscle biopsy samples utilizing an untargeted LC-MS/MS-based proteomics approach. [PDF]

Anal Bioanal Chem, 2023
Brockbals L, Garrett-Rickman S, Fu S, Ueland M, McNevin D, Padula MP.   +5 more
europepmc   +1 more source

Contracture test and histologic and histochemical analyses of muscle biopsy specimens from horses with exertional rhabdomyolysis [PDF]

, 1990
S. V. HILDEBRAND, D. Arpin, George H. Cardinet   +2 more
openalex   +1 more source

Artificial Intelligence‐Assisted Urine Cytology for Noninvasive Detection of Muscle‐Invasive Urothelial Carcinoma: A Multi‐Center Diagnostic Study with Prospective Validation

Advanced Science, EarlyView.
Accurate preoperative detection of muscle‐invasive urothelial carcinoma (MIUC) is crucial for clinical decision‐making. This study developed PUCAS‐M, an artificial intelligence (AI) model that analyzes urine cytology to assist in differentiating MIUC from non‐MIUC.
Runnan Shen, Fan Jiang, Xiaowei Huang, Guibin Hong, Yun Luo, Huan Wan, Ye Xie, Mengyi Zhu, Yun Wang, Bohao Liu, Ping Qin, Yahui Wang, Haoxuan Wang, Hongkun Yang, Zhen Lin, Rui Chen, Nengtai Ouyang, Jian Huang, Tianxin Lin, Shaoxu Wu   +19 more
wiley   +1 more source

A 10‐Year Longitudinal Study of Muscle Morphology and Performance in Masters Sprinters

Journal of Cachexia, Sarcopenia and Muscle
Background Both longitudinal and cross‐sectional studies have demonstrated that muscle mass, strength and power are lost with ageing. Although longitudinal studies have shown changes in muscle morphology and function in sedentary, healthy active and ...
P. W. Hendrickse, B. Hutz, M. T. Korhonen, H. Degens   +3 more
doaj   +1 more source

Intranuclear inclusions in muscle biopsy can differentiate oculopharyngodistal myopathy and oculopharyngeal muscular dystrophy. [PDF]

Acta Neuropathol Commun, 2022
Ogasawara M, Eura N, Iida A, Kumutpongpanich T, Minami N, Nonaka I, Hayashi S, Noguchi S, Nishino I.   +8 more
europepmc   +1 more source

Sternohyoid Muscle Biopsy [PDF]

, 1991
Gloria Galloway, Fred G. Fedok, David A. Wiegand, Javad Towfighi   +3 more
openalex   +1 more source

Essential Updates 2023/2024: Recent Advances of Multimodal Approach in Patients for Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Gastric cancer remains a major global health burden, especially in East Asia. Recent years have brought significant advances in multimodal management, including surgery, perioperative chemotherapy, immunotherapy, and supportive care. This review summarizes key updates from 2023 to 2024, focusing on surgical innovations, perioperative systemic ...
Katsutoshi Shoda, Yoshihiko Kawaguchi, Suguru Maruyama, Daisuke Ichikawa   +3 more
wiley   +1 more source

Myotonia congenita and myoadenylate deaminase deficiency: case report

Arquivos de Neuro-Psiquiatria, 2003
Approximately 1-2% of the population has a deficiency of the enzyme myoadenylate deaminase. Early reports suggested that patients with myoadenylate deaminase deficiency had various forms of myalgia, and exercise intolerance.
Scola Rosana Herminia, Iwamoto Fabio Massaiti, Camargo Carlos Henrique, Arruda Walter Oleschko, Werneck Lineu Cesar   +4 more
doaj  

Regulating the Interaction Between Near‐Infrared Dye and Endogenous Albumin for Concurrent Imaging Skin Inflammation and Neovascularization After Flap Transplantation

Aggregate, EarlyView.
This study identified a near‐infrared (NIR) dye with superior covalent albumin‐binding capability, enabling high‐contrast imaging of skin inflammation with minimal background interference. This work further demonstrated dual‐channel imaging of skin barrier disruption and neovascularization in flap transplantation models, and allowed simultaneous ...
Yijing Du, Xue Zheng, Yanli Gao, Zetao Dang, Yuewei Zhang, Shoujun Zhu   +5 more
wiley   +1 more source