Low-intensity muscle contraction exercise reduces pain sensitivity by modulating peripheral pathology and spinal sensitization in end-stage knee osteoarthritis rats. [PDF]
Motokawa S +6 more
europepmc +1 more source
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source
The Twisting and Untwisting of Actin and Tropomyosin Filaments Are Involved in the Molecular Mechanisms of Muscle Contraction, and Their Disruption Can Result in Muscle Disorders. [PDF]
Borovikov YS +4 more
europepmc +1 more source
Prior Expectations Bias Confidence Judgments Through Parietal Alpha‐Band Modulation
ABSTRACT Humans possess the metacognitive ability to estimate the likely accuracy of their own decisions through confidence judgments. Yet, whether prior information shapes confidence and the neural mechanisms mediating such influence, remain to be determined.
Luca Tarasi +4 more
wiley +1 more source
Editorial: Biophysics of muscle contraction
Alexandre Lewalle
doaj +1 more source
Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction. [PDF]
Liu G +6 more
europepmc +1 more source
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick +8 more
wiley +1 more source
An <i>in silico</i> pipeline identifies new neuropeptides and reveals a non-amidated regulator of muscle contraction in the freshwater cnidarian <i>Hydra</i>. [PDF]
Prabhu P, Reddy PC.
europepmc +1 more source
Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou +12 more
wiley +1 more source
Targeting cytoskeletal biomechanics to modulate airway smooth muscle contraction in asthma. [PDF]
McCullough M +5 more
europepmc +1 more source

