Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Motor Adaptations to Pain during a Bilateral Plantarflexion Task: Does the Cost of Using the Non-Painful Limb Matter? [PDF]
, 2016 During a force-matched bilateral task, when pain is induced in one limb, a shift of load to the non-painful leg is classically observed. This study aimed to test the hypothesis that this adaptation to pain depends on the mechanical efficiency of the non ...
Carroll, Timothy J. +6 more
core +9 more sources
Active: journal of physical education, sport, health and recreation, 2020 In playing basketball, a factor that has been ignored by the students is the effect of the strength of leg muscle and eye-hand coordination in shooting free throws.
Novriansyah Novriansyah +4 more
doaj +1 more source
Sex Differences in Spatial Accuracy Relate to the Neural Activation of Antagonistic Muscles in Young Adults [PDF]
, 2017 Sex is an important physiological variable of behavior, but its effect on motor control remains poorly understood. Some evidence suggests that women exhibit greater variability during constant contractions and poorer accuracy during goal-directed tasks ...
Casamento-Moran, Agostina +6 more
core +1 more source
On Neuromechanical Approaches for the Study of Biological Grasp and Manipulation
, 2017 Biological and robotic grasp and manipulation are undeniably similar at the level of mechanical task performance. However, their underlying fundamental biological vs.
Santello, Marco +1 more
core +1 more source
Effects of hemodialysis therapy on sit-to-walk characteristics in end stage renal disease patients [PDF]
, 2012 Patients with end stage renal diseases (ESRD) undergoing hemodialysis (HD) have high morbidity and mortality due to multiple causes; one of which is dramatically higher fall rates than the general population.
Abdel-Rahman, Emaad +3 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Between-subject variability of muscle synergies during a complex motor skill
Frontiers in Computational Neuroscience, 2012 The purpose of the present study was to determine whether subjects who have learned a complex motor skill exhibit similar neuromuscular control strategies. We studied a population of experienced gymnasts during backward giant swings on the high bar. This
Julien eFrère, François eHug
doaj +1 more source
The slow sarco/endoplasmic reticulum Ca2+-ATPase declines independently of slow myosin in soleus muscle of diabetic rats [PDF]
, 2009 The sarcoplasmic reticulum Ca2+-ATPase (SERCA) isoforms are normally expressed in coordination with the corresponding myosin heavy chain (MyHC) isoforms in the fibers of skeletal muscle but this coordination is often disrupted in pathological conditions.
Rácz, Gábor +3 more
core
The Effects of Lesions in the Dorsolateral Pons on the Coordination of Swallowing and Breathing in Awake Goats [PDF]
, 2011 The purpose of this retrospective study was to gain insight into the contribution of the dorsolateral pons to the coordination of swallowing and breathing in awake goats.
Bonis, Joshua M. +7 more
core +2 more sources